Evidence map›Paper›PMID 24956164›Full record

ArticleJournal of functional biomaterials2011

Mechanotransduction: tuning stem cells fate.

Francesco D'Angelo, Roberto Tiribuzi, Ilaria Armentano, Josè Maria Kenny, Sabata Martino, Aldo Orlacchio

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Non-transport functions of motor proteins in corticogenesis.Frontiers in cell and developmental biology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Regulation of Limbal Epithelial Stem Cells: Importance of the Niche.International journal of molecular sciences · 2021
    Review
  10. Article
  11. Intrinsic Mechanical Cues and Their Impact on Stem Cells and Embryogenesis.Frontiers in cell and developmental biology · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Adipose Stem Cell Translational Applications: From Bench-to-Bedside.International journal of molecular sciences · 2018
    Review
  18. Article
  19. Nanocomposites Based on Biodegradable Polymers.Materials (Basel, Switzerland) · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesco D'AngeloDepartment of Experimental Medicine and Biochemical Science, Section of Biochemistry and Molecular Biology, University of Perugia, Via del Giochetto, 06126 Perugia, Italy. francescodangelo@hotmail.it.
Roberto TiribuziDepartment of Experimental Medicine and Biochemical Science, Section of Biochemistry and Molecular Biology, University of Perugia, Via del Giochetto, 06126 Perugia, Italy. robertotiribuzi@yahoo.it.
Ilaria ArmentanoMaterials Engineering Centre, UdR INSTM, NIPLAB, University of Perugia, Strada di Pentima 4, 05100 Terni, Italy. ilaria.armentano@unipg.it.
Josè Maria KennyMaterials Engineering Centre, UdR INSTM, NIPLAB, University of Perugia, Strada di Pentima 4, 05100 Terni, Italy. jkenny@unipg.it.
Sabata MartinoDepartment of Experimental Medicine and Biochemical Science, Section of Biochemistry and Molecular Biology, University of Perugia, Via del Giochetto, 06126 Perugia, Italy. martinos@unipg.it.
Aldo OrlacchioDepartment of Experimental Medicine and Biochemical Science, Section of Biochemistry and Molecular Biology, University of Perugia, Via del Giochetto, 06126 Perugia, Italy. orly@unipg.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is a general concern that the success of regenerative medicine-based applications is based on the ability to recapitulate the molecular events that allow stem cells to repair the damaged tissue/organ. To this end biomaterials are designed to display properties that, in a precise and physiological-like fashion, could drive stem cell fate both in vitro and in vivo. The rationale is that stem cells are highly sensitive to forces and that they may convert mechanical stimuli into a chemical response. In this review, we describe novelties on stem cells and biomaterials interactions with more focus on the implication of the mechanical stimulation named mechanotransduction.

Identifiers

PMID24956164
PMCPMC4030896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.