Evidence map›Paper›PMID 24955381›Full record

ArticleMovement disorders clinical practice2014

Sleep Disorders in Atypical Parkinsonism.

Sabra M Abbott, Aleksandar Videnovic

Open access · bronzeAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Stage-specific interactions among PLM, RBD, and OSAHS in parkinson's disease and MSA.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Sleep Dysfunction in Movement Disorders: a Window to the Disease Biology.Current neurology and neuroscience reports · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Current Management and Emerging Therapies in Multiple System Atrophy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020
    Review
  18. Article
  19. Sleep as a Therapeutic Target in the Aging Brain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sabra M AbbottDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Aleksandar VidenovicDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Harvard University · USNorthwestern University · US

Funding

TRAINING PROGRAM IN THE NEUROSCIENCE OF HUMAN COGNITIONT32NS047987 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Rodrigo M Braga, Christina Maria Zelano · 2006 to 2026
$5.6M
Circadian Rhythms and Sleep-Wake Cycles in Parkinson's DiseaseK23NS072283 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI VIDENOVIC, ALEKSANDAR · 2012 to 2017
$935k
Cholinergic Regulation of Sleep and Circadian RhythmsF30NS047802 · NINDS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI ABBOTT, SABRA M · 2004 to 2007
$282k
NINDS NIH HHS F30 NS047802NINDS NIH HHS K23 NS072283NINDS NIH HHS T32 NS047987
6 · The paper itself

Abstract

Sleep disorders are commonly seen in atypical parkinsonism, with particular disorders occurring more frequently in specific parkinsonian disorders. Multiple systems atrophy (MSA) is a synucleinopathy often associated with nocturnal stridor which is a serious, but treatable condition highly specific to MSA. In addition, this disorder is strongly associated with rapid eye movement (REM) sleep behavior disorder (RBD), which is also seen in dementia with Lewy bodies (DLB). RBD is far less prevalent in progressive supranuclear palsy (PSP), which is a tauopathy. Insomnia and impaired sleep architecture are the most common sleep abnormalities seen in PSP. Corticobasilar degeneration (CBD) is also a tauopathy, but has far fewer sleep complaints associated with it than PSP. In this manuscript we review the spectrum of sleep dysfunction across the atypical parkinsonian disorders, emphasize the importance of evaluating for sleep disorders in patients with parkinsonian symptoms, and point to sleep characteristics that can provide diagnostic clues to the underlying parkinsonian disorder.

Indexed as

corticobasal degenerationdementia with lewy bodiesinsomniamultiple system atrophyprogressive supranuclear palsyREM sleep behavior disorderSleep disorders

Identifiers

PMID24955381
PMCPMC4061748
OpenAlexW2082153174

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.