ArticleAnnual review of statistics and its application2014
Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data.
Article in Annual review of statistics and its application, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Cerebrospinal fluid inflammatory proteomic profiling identifies biomarkers linked to disease progression in amyotrophic lateral sclerosis.Journal of neurology · 2026Article
- Article
- TARGETING UNDERREPRESENTED POPULATIONS IN PRECISION MEDICINE: A FEDERATED TRANSFER LEARNING APPROACH.The annals of applied statistics · 2023Article
- Inflammatory Biomarkers in Newly Diagnosed Patients With Parkinson Disease and Related Neurodegenerative Disorders.Neurology(R) neuroimmunology & neuroinflammation · 2023Article
- Understanding the impact of correlation within pair-bonds on Cormack-Jolly-Seber models.Ecology and evolution · 2021Article
- Sparse Regression in Cancer Genomics: Comparing Variable Selection and Predictions in Real World Data.Cancer informatics · 2021Article
- Pan-Genomic and Polymorphic Driven Prediction of Antibiotic Resistance inFrontiers in microbiology · 2019Article
- Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III.Ophthalmology · 2019Article
- Dopaminergic and Opioid Pathways Associated with Impulse Control Disorders in Parkinson's Disease.Frontiers in neurology · 2018Article
- Iterative hard thresholding for model selection in genome-wide association studies.Genetic epidemiology · 2017Article
- Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data.Genetic epidemiology · 2017Article
- Transforming big data into computational models for personalized medicine and health care.Dialogues in clinical neuroscience · 2016Review
- The use of vector bootstrapping to improve variable selection precision in Lasso models.Statistical applications in genetics and molecular biology · 2016Article
- Genome-wide QTL and eQTL analyses using Mendel.BMC proceedings · 2016Article
- Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium.PloS one · 2016Article
- Matrix Completion Discriminant Analysis.Computational statistics & data analysis · 2015Article
- Detecting the Genomic Signature of Divergent Selection in Presence of Gene Flow.Current genomics · 2015Article
- Genome scans for detecting footprints of local adaptation using a Bayesian factor model.Molecular biology and evolution · 2014Article
- Finding genomic function for genetic associations in nicotine addiction research: the ENCODE project's role in future pharmacogenomic analysis.Pharmacology, biochemistry, and behavior · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Statistical genetics is undergoing the same transition to big data that all branches of applied statistics are experiencing. With the advent of inexpensive DNA sequencing, the transition is only accelerating. This brief review highlights some modern techniques with recent successes in statistical genetics. These include: (a) lasso penalized regression and association mapping, (b) ethnic admixture estimation, (c) matrix completion for genotype and sequence data, (d) the fused lasso and copy number variation, (e) haplotyping, (f) estimation of relatedness, (g) variance components models, and (h) rare variant testing. For more than a century, genetics has been both a driver and beneficiary of statistical theory and practice. This symbiotic relationship will persist for the foreseeable future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.