Evidence map›Paper›PMID 24955359›Full record

ReviewBioMed research international2014

Pharmacological treatments in gambling disorder: a qualitative review.

Matteo Lupi, Giovanni Martinotti, Tiziano Acciavatti, Mauro Pettorruso, Marcella Brunetti, Rita Santacroce, Eduardo Cinosi, Giuseppe Di Iorio, Marco Di Nicola, Massimo Di Giannantonio

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Gambling disorder comorbidity a narrative review.Dialogues in clinical neuroscience · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matteo LupiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.
Giovanni MartinottiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.
Tiziano AcciavattiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.
Mauro PettorrusoDepartment of Psychiatry, Drug Addiction Unit, Catholic University Medical School, Rome, Italy.ORCID 0000-0002-4164-3040
Marcella BrunettiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.
Rita SantacroceDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.ORCID 0000-0003-1377-9183
Eduardo CinosiDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.
Giuseppe Di IorioDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.
Marco Di NicolaDepartment of Psychiatry, Drug Addiction Unit, Catholic University Medical School, Rome, Italy.
Massimo Di GiannantonioDepartment of Neuroscience and Imaging, University "G. d'Annunzio", Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gambling disorder (GD) is a psychiatric condition associated with both social and family costs; DSM-5 currently includes GD among addictive disorders. Despite the high burden of this condition, to date there are no treatment guidelines approved by Food and Drug Administration (FDA). Purpose of this paper is to offer a qualitative overview about the different pharmacologic agents used for the treatment of GD. Our analysis, conducted on a final selection of 75 scientific papers, demonstrates that a variety of pharmaceutical classes have been utilised, with different results. Published data, although limited by brief duration of the studies and small number of enrolled subjects, shows mixed evidence for serotonergic antidepressants, opioid antagonists, and mood stabilizers. Other compounds, such as glutamatergic agents and psychostimulants, deserve further studies.

Indexed as

Antipsychotic AgentsBehavior, AddictiveExcitatory Amino Acid AgentsGamblingHumansUnited StatesUnited States Food and Drug AdministrationAntipsychotic AgentsExcitatory Amino Acid Agents

Identifiers

PMID24955359
PMCPMC4052082

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.