ReviewEndoscopic ultrasound2014
Can elastography replace fine needle aspiration?
Review in Endoscopic ultrasound, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- The efficiency of contrast-enhanced endoscopic ultrasound (EUS) combined with EUS elastography for pancreatic cancer diagnosis: a systematic review and meta-analysis.Ultrasonography (Seoul, Korea) · 2023Pooled it
- Utilization of lymph node elastography in the axillary staging of breast cancer.Frontiers in oncology · 2025Article
- A case of acute lymphoblastic leukaemia disease with pancreatic mass as the first symptom confirmed by elastography combined with EUS-FNA.The Journal of international medical research · 2022Article
- Nonalcoholic fatty pancreas disease: An emerging clinical challenge.World journal of clinical cases · 2021Review
- Echoendoscopy with elastography in mediastinal lymph nodes.Einstein (Sao Paulo, Brazil) · 2019Article
- Technique of qualitative and semiquantitative EUS elastography in pancreatic examination.Endoscopic ultrasound · 2017Article
- The Clinical Implications of Fatty Pancreas: A Concise Review.Digestive diseases and sciences · 2017Review
- Ultrasound Elastography: Review of Techniques and Clinical Applications.Theranostics · 2017Review
- The Role of Real Time Endoscopic Ultrasound Guided Elastography for Targeting EUS-FNA of Suspicious Pancreatic Masses: A Review of the Literature and A Single Center Experience.JOP : Journal of the pancreas · 2016Article
- Elastography for the pancreas: Current status and future perspective.World journal of gastroenterology · 2016Review
- Endoscopic ultrasound elastography: Current status and future perspectives.World journal of gastroenterology · 2015Review
- Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography.Journal of thoracic disease · 2015Review
- Convex probe endobronchial ultrasound: applications beyond conventional indications.Journal of thoracic disease · 2015Review
- New endoscopic ultrasound techniques for digestive tract diseases: A comprehensive review.World journal of gastroenterology · 2015Review
- Endoscopic ultrasound elastography strain histograms in the evaluation of patients with pancreatic masses.World journal of gastroenterology · 2015Article
- Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparison of the clinicopathologic features and prognosis.Journal of thoracic disease · 2014Article
- "Invisible" pancreatic masses identified by EUS by the "ductal cutoff sign".Endoscopic ultrasoundArticle
- A quarter century of EUS-FNA: Progress, milestones, and future directions.Endoscopic ultrasoundReview
- Endoscopic Ultrasound in the Diagnosis and Staging of Pancreatic Cancer.GE Portuguese journal of gastroenterologyReview
- Endoscopic ultrasound: Elastographic lymph node evaluation.Endoscopic ultrasoundArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endoscopic ultrasound (EUS) is one of the best diagnostic methods for diseases of the digestive tract and surrounding organs. Whereas EUS-guided fine needle aspiration (FNA) has been very useful for providing histological confirmation for previously hard to reach lesions, elastography is aiming to obtain a "virtual biopsy" by assessing differences in elasticity between the normal and pathological - usually malignant - tissue. A question that arises is whether EUS-elastography has reached a stage where it might successfully supplant the use of EUS-FNA in some of its clinical indications. The main indications of EUS-guided FNA are listed in this article and published data on the usage of elastography in these settings is reviewed for each one. In some of the indications, a plethora of studies have been published, notably for the evaluation of solid pancreatic masses and lymph nodes, while in others there is little relevant data (submucosal masses, left liver lesions, left adrenal masses), or elastography simply is not suitable as a diagnostic means (cystic lesions). Our conclusion is that elastography is not yet ready to replace EUS-FNA in its indications, but should complement it in various settings, especially for the assessment of lymph nodes. It can only be considered an alternative on a case-by-case basis, in situations where FNA is regarded as a contraindication. Furthermore, it could be used in conjunction with other imaging techniques, such as contrast-enhanced EUS, in order to further improve the accuracy of non-invasive EUS assessment, possibly making the case for a more limited or targeted use of EUS-FNA in selected cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.