ArticleInternational journal of clinical and experimental medicine2014
Evaluation of mean platelet volume in patients with type 2 diabetes mellitus and blood glucose regulation: a marker for atherosclerosis?
Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04971252 (Impact of Type II Diabetes Mellitus on Basic Coagulation Profile and Platelet Indices in Non-dialysis Chronic Kidney Disease Patients), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Type II Diabetes Mellitus on Basic Coagulation Profile and Platelet Indices in Non-dialysis Chronic Kidney Disease Patients
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Effects of statin therapy on mean platelet volume in patients with risk of cardiovascular diseases: a systematic review and meta-analysis.Bioscience reports · 2019Pooled it
- The association of plasma level of phenylalanine with inflammatory markers, insulin resistance, and atherosclerotic indexes in patients with phenylketonuria.Journal of diabetes and metabolic disorders · 2025Article
- The effect of coagulation traits on the risk of retinal vein occlusion: a mendelian randomization study.Scientific reports · 2025Article
- Association between hematological indices and blood glucose level among patients with type 2 diabetes.Irish journal of medical science · 2024Article
- Associations Between Mean Platelet Volume and Various Factors in Type 2 Diabetes Patients: A Single-Center Study from Poland.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Evaluation of the relation between HBA1C and MPV, PDW levels of patients with Type 2 diabetes admitted in internal medicine polyclinics.Northern clinics of Istanbul · 2023Article
- Hematological indices and their correlation with glucose control parameters in a prediabetic rat model.Veterinary world · 2022Article
- Platelet and Thrombophilia-Related Risk Factors of Retinal Vein Occlusion.Journal of clinical medicine · 2021Review
- Platelet adhesion in type 2 diabetes: impact of plasma albumin and mean platelet volume.Thrombosis journal · 2021Article
- Assessment of hematologic indices and their correlation to hemoglobin A1c among Bosnian children with type 1 diabetes mellitus and their healthy peers.Journal of medical biochemistry · 2021Article
- Basic Coagulation Profiles and Platelet Parameters Among Adult Type 1 and Type 2 Diabetes Patients at Dessie Referral Hospital, Northeast Ethiopia: Comparative Cross-Sectional Study.Journal of blood medicine · 2021Article
- High mean platelet volume-to-platelet count ratio as a diagnostic maker for increased risk of liver function damage in pediatric patients with infectious mononucleosis in China.Experimental and therapeutic medicine · 2019Article
- Mean platelet volume and coronary plaque vulnerability: an optical coherence tomography study in patients with non-ST-elevation acute coronary syndrome.BMC cardiovascular disorders · 2019Observational
- Polysaccharide peptide (PsP) GVascular health and risk management · 2019Article
- Mean platelet volume and platelet distribution width levels in patients with mild psoriasis vulgaris with metabolic syndrome.Postepy dermatologii i alergologii · 2018Article
- Comparison of Platelet Distribution Width and CA19-9 in Resectable Pancreas Cancer.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2018Article
- A Study of Platelet Indices in Type 2 Diabetes Mellitus Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2018Article
- Focusing on a complete blood cell parameter: mean platelet volume levels may be a predictor of coronary slow flow.Vascular health and risk management · 2017Article
- Mean Platelet Volume and Immature Platelet Fraction in Autoimmune Disorders.Frontiers in medicine · 2017Review
- Hematological indices and their correlation with fasting blood glucose level and anthropometric measurements in type 2 diabetes mellitus patients in Gondar, Northwest Ethiopia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePlatelets have an important role in atherosclerosis and arterial thrombosis. Cardiovascular complication prevalence of type 2 diabetes mellitus (type 2 DM) may be associated with glycosylated hemoglobin (HbA1c) and mean platelet volume (MPV). The aim of the study was to investigate if platelets were activated in diabetes and its associated vascular complications by measuring the MPV in the diabetics compared to the non-diabetics, and to determine the correlation of MPV with fasting serum glucose (FSG), HbA1c and duration of diabetes in the diabetic patients, respectively. MATERIALS AND
methodsThe study carried out in 65 patients with type 2 DM and 40 non-diabetic subjects. In addition to non-diabetic patients, all diabetic patients were divided into two groups according to their HbA1c levels: group A consisted of patients with HbA1c levels ≤7% and group B consisted of patients with HbA1c levels >7%.
resultsMPV was significantly higher in Group B as compared to both non-diabetics and Group A. MPV had a high positive correlation with HbA1c and FSG, as with diabetes duration. It is found that MPV was increased in type 2 DM.
conclusionOur findings suggested an association between MPV and HbA1c. Therefore, MPV would be a beneficial prognostic marker of cardio-vascular complications in patients with type 2 DM.
Indexed as
Identifiers
24955167PMC4057846W1903180055What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.