ReviewTrends in parasitology2014
The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.
Review in Trends in parasitology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prevalence of Leishmania RNA virus in cutaneous leishmaniasis: a meta-analysis and systematic review.BMC infectious diseases · 2025Pooled it
- Impact of Bacterial Membrane Vesicles on Cellular Responses in Leishmania amazonensis-Infected Macrophages In Vitro.Scandinavian journal of immunology · 2026Article
- Clinical and immunological spectra of human cutaneous leishmaniasis in North Africa and French Guiana.Frontiers in immunology · 2023Review
- An In-depth Proteomic Map of Leishmania donovani Isolate from Post Kala-azar Dermal Leishmaniasis (PKDL) Patient.Acta parasitologica · 2022Article
- Toll-Like Receptor- and Protein Kinase R-Induced Type I Interferon Sustains Infection ofFrontiers in immunology · 2022Article
- Dissection of the macrophage response towards infection by theFrontiers in cellular and infection microbiology · 2022Article
- In and out:Frontiers in cellular and infection microbiology · 2022Article
- Article
- Gasdermins in Innate Host Defense AgainstFrontiers in immunology · 2022Review
- The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism.PLoS pathogens · 2021Article
- The Presence ofFrontiers in cellular and infection microbiology · 2021Article
- Interleukin-4 Responsive Dendritic Cells Are Dispensable to Host Resistance AgainstFrontiers in immunology · 2021Article
- Article
- Tracking of quiescence in Leishmania by quantifying the expression of GFP in the ribosomal DNA locus.Scientific reports · 2019Article
- Molecular Characterization ofGenes · 2019Article
- TLR9/MyD88/TRIF signaling activates host immune inhibitory CD200 in Leishmania infection.JCI insight · 2019Article
- Impaired activation of lesional CD8Scientific reports · 2019Article
- Understanding Resistance vs. Susceptibility in Visceral Leishmaniasis Using Mouse Models ofFrontiers in cellular and infection microbiology · 2019Article
- RNA Viruses inmBio · 2018Article
- Concentration of 2'C-methyladenosine triphosphate byThe Journal of biological chemistry · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cutaneous leishmaniases have persisted for centuries as chronically disfiguring parasitic infections affecting millions of people across the subtropics. Symptoms range from the more prevalent single, self-healing cutaneous lesion to a persistent, metastatic disease, where ulcerations and granulomatous nodules can affect multiple secondary sites of the skin and delicate facial mucosa, even sometimes diffusing throughout the cutaneous system as a papular rash. The basis for such diverse pathologies is multifactorial, ranging from parasite phylogeny to host immunocompetence and various environmental factors. Although complex, these pathologies often prey on weaknesses in the innate immune system and its pattern recognition receptors. This review explores the observed and potential associations among the multifactorial perpetrators of infectious metastasis and components of the innate immune system.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.