ArticleFungal genetics and biology : FG & B2014
The Neurospora crassa CPS-1 polysaccharide synthase functions in cell wall biosynthesis.
Article in Fungal genetics and biology : FG & B, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Characterization of the Polysaccharide and Protein Composition ofJournal of fungi (Basel, Switzerland) · 2026Article
- Characterization of theCell surface (Amsterdam, Netherlands) · 2025Article
- srdA mutations suppress the rseA/cpsA deletion mutant conidiation defect in Aspergillus nidulans.Scientific reports · 2023Article
- Effect of itaconic acid production on Neurospora crassa in consolidated bioprocessing of cellulose.Microbial cell factories · 2023Article
- Evidencing New Roles for the Glycosyl-Transferase Cps1 in the Phytopathogenic FungusJournal of fungi (Basel, Switzerland) · 2022Article
- Article
- The putative polysaccharide synthase AfCps1 regulates Aspergillus fumigatus morphogenesis and conidia immune response in mouse bone marrow-derived macrophages.Journal of microbiology (Seoul, Korea) · 2021Article
- Off the wall: The rhyme and reason ofCell surface (Amsterdam, Netherlands) · 2019Review
- Article
- The Glycosylphosphatidylinositol-AnchoredmSphere · 2019Article
- The Genetics and Biochemistry of Cell Wall Structure and Synthesis inFrontiers in microbiology · 2019Review
- Article
- cpsA regulates mycotoxin production, morphogenesis and cell wall biosynthesis in the fungus Aspergillus nidulans.Molecular microbiology · 2017Article
- Genetic and biochemical characterization of the GH72 family of cell wall transglycosylases in Neurospora crassa.Fungal genetics and biology : FG & B · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The Neurospora crassa cps-1 gene encodes a polysaccharide synthase with homology to the Cryptococcus neoformans hyaluronic acid synthase Cps1p. Homologs of the cps-1 gene are found in the genomes of many fungi. Loss of CPS-1 results in a cell wall defect that affects all stages of the N. crassa life cycle, including vegetative growth, protoperithecia (female mating structure) development, and conidia (asexual spore) development. The cell wall of cps-1 deletion mutants is sensitive to cell wall perturbation reagents. Our results demonstrate that CPS-1 is required for the incorporation of cell wall proteins into the cell wall and plays a critical role in cell wall biogenesis. We found that the N. crassa cell wall is devoid of hyaluronic acid, and conclude that the polysaccharide produced by the CPS-1 is not hyaluronic acid.
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Registered trials
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