ReviewClinical rheumatology2015
The labyrinth of autoinflammatory disorders: a snapshot on the activity of a third-level center in Italy.
Review in Clinical rheumatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Advances in the Multimodality Imaging and Management of Recurrent Pericarditis: A Contemporary Review.Current cardiology reports · 2024Review
- Risk for cancer development in familial Mediterranean fever and associated predisposing factors: an ambidirectional cohort study from the international AIDA Network registries.Frontiers in immunology · 2024Article
- Can Asthma Cause Pericardial Effusion? Insights Into an Intriguing Association.Texas Heart Institute journal · 2023Article
- FMF is not always "fever": from clinical presentation to "treat to target".Italian journal of pediatrics · 2020Review
- IL-1 Inhibitors in the Treatment of Monogenic Periodic Fever Syndromes: From the Past to the Future Perspectives.Frontiers in immunology · 2020Review
- Periodic fever syndromes and the autoinflammatory diseases (AIDs).Journal of translational autoimmunity · 2020Review
- Unveiling the Efficacy, Safety, and Tolerability of Anti-Interleukin-1 Treatment in Monogenic and Multifactorial Autoinflammatory Diseases.International journal of molecular sciences · 2019Review
- Treating the Different Phenotypes of Behçet's Syndrome.Frontiers in immunology · 2019Review
- Recurrent Pericarditis in Children and Adolescents.Frontiers in pediatrics · 2019Review
- Recurrent pericarditis: still idiopathic? The pros and cons of a well-honoured term.Internal and emergency medicine · 2018Review
- Management of idiopathic recurrent pericarditis in adults and in children: a role for IL-1 receptor antagonism.Internal and emergency medicine · 2018Review
- The diagnostic evaluation of patients with a suspected hereditary periodic fever syndrome: experience from a referral center in Italy.Internal and emergency medicine · 2017Article
- Diagnostic Criteria for Adult-Onset Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome.Frontiers in immunology · 2017Article
- Lung Involvement in Children with Hereditary Autoinflammatory Disorders.International journal of molecular sciences · 2016Review
- Systemic and organ involvement in monogenic autoinflammatory disorders: a global review filtered through internists' lens.Internal and emergency medicine · 2016Review
- Anakinra as a diagnostic challenge and treatment option for systemic autoinflammatory disorders of undefined etiology.JCI insight · 2016Article
- Immunometabolic biomarkers of inflammation in Behçet's disease: relationship with epidemiological profile, disease activity and therapeutic regimens.Clinical and experimental immunology · 2016Article
- Lights and shadows in autoinflammatory syndromes from the childhood and adulthood perspective.Clinical rheumatology · 2016Review
- PFAPA syndrome and Behçet's disease: a comparison of two medical entities based on the clinical interviews performed by three different specialists.Clinical rheumatology · 2016Article
- Development of de novo major involvement during follow-up in Behçet's syndrome.Clinical rheumatology · 2016Article
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoinflammatory disorders (AIDs) are a novel class of diseases elicited by mutations in genes regulating the homeostasis of innate immune complexes, named inflammasomes, which lead to uncontrolled oversecretion of the proinflammatory cytokine interleukin-1β. Protean inflammatory symptoms are variably associated with periodic fever, depicting multiple specific conditions. Childhood is usually the lifetime in which most hereditary AIDs start, though still a relevant number of patients may experience a delayed disease onset and receive a definite diagnosis during adulthood. As a major referral laboratory for patients with recurrent fevers, we have tested samples from 787 patients in the period September 2007-March 2014, with a total of 1,328 AID-related genes evaluated and a gene/patient ratio of 1.69. In this report, we describe our experience in the clinical approach to AIDs, highlight the most striking differences between child and adult-onset AIDs, and shed an eye-opening insight into their diagnostic process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.