Evidence map›Paper›PMID 24953168›Full record

ArticleJournal of substance abuse treatment2014

Emerging adult age status predicts poor buprenorphine treatment retention.

Zev Schuman-Olivier, Roger D Weiss, Bettina B Hoeppner, Jacob Borodovsky, Mark J Albanese

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 75 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02778282 nacompletednot on this mapstarted 2017, after this paper: background citation

MySafeRx™: An Integrated Mobile Platform for Buprenorphine Adherence

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2017 to 2021Enrolled27ConditionsOpioid Use DisorderArmsMySafeRx™
NCT02942199 nacompletednot on this mapstarted 2016, after this paper: background citation

MySafeRx & MedicaSafe Open-Label Buprenorphine Induction and Lapse Evaluation (MyMOBILE)

TypeinterventionalSponsorCambridge Health AllianceRan2016 to 2018Enrolled12ConditionsOpioid Use DisorderArmsMySafeRx
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 4 syntheses or guidelines pooled it, 123 citations in OpenAlex.

  1. Pooled it
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  4. Risk Factors for Drug Overdose in Young People: A Systematic Review of the Literature.Journal of child and adolescent psychopharmacology · 2019
    Pooled it
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  6. Extended-release naltrexone for youth with opioid use disorder.Journal of substance abuse treatment · 2021
    Trial
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zev Schuman-OlivierDepartment of Psychiatry, Cambridge Health Alliance, Harvard Medical School, United States; Psychiatric Research Center, Geisel School of Medicine at Dartmouth, United States. Electronic address: zschuman@cha.harvard.edu.
Roger D WeissDepartment of Psychiatry, McLean Hospital, Harvard Medical School, United States.
Bettina B HoeppnerDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, United States.
Jacob BorodovskyDepartment of Psychiatry, Cambridge Health Alliance, Harvard Medical School, United States.
Mark J AlbaneseDepartment of Psychiatry, Cambridge Health Alliance, Harvard Medical School, United States.
Cambridge Health Alliance · USHarvard University · US

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
The National Drug Abuse Treatment Clinical Trials Network (U10)U10DA015831 · NIDA · MC LEAN HOSPITAL (BELMONT, MA) · PI CARROLL, KATHLEEN M., WEISS, ROGER D. · 2002 to 2015
$28.8M
Mentoring in Drug Abuse and Dual Diagnosis ResearchK24DA022288 · NIDA · MCLEAN HOSPITAL · PI WEISS, ROGER D. · 2007 to 2016
$1.8M
Dynamic Processes of Smoking CessationK01DA027097 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HOEPPNER, BETTINA B. · 2010 to 2014
$834k
NCRR NIH HHS UL1 RR025758NCRR NIH HHS UL1RR025758NIDA NIH HHS K01 DA027097NIDA NIH HHS K01DA027097NIDA NIH HHS K24 DA022288NIDA NIH HHS K24DA022288NIDA NIH HHS L30 DA027330NIDA NIH HHS U10 DA015831NIDA NIH HHS U10 DA15831
6 · The paper itself

Abstract

Emerging adults (18-25 years old) are often poorly retained in substance use disorder treatment. Office-based buprenorphine often enhances treatment retention among people with opioid dependence. In this study, we examined the records of a collaborative care buprenorphine treatment program to compare the treatment retention rates of emerging adults versus older adults. Subjects were 294 adults, 71 (24%) aged 18-25, followed in treatment with buprenorphine, nurse care management, and an intensive outpatient program followed by weekly psychosocial treatment. Compared to older adults, emerging adults remained in treatment at a significantly lower rate at 3 months (56% versus 78%) and 12 months (17% versus 45%), and were significantly more likely to test positive for illicit opioids, relapse, or drop out of treatment. Further research into factors associated with buprenorphine treatment retention among emerging adults is needed to improve treatment and long-term outcomes in this group.

Indexed as

AdolescentAdultAgingBuprenorphineFemaleHumansMaleNarcotic AntagonistsOpioid-Related DisordersPatient CompliancePatient DropoutsRecurrenceRetrospective StudiesSubstance Abuse DetectionTreatment OutcomeYoung AdultBuprenorphineNarcotic AntagonistsBuprenorphineDevelopmentEmerging adultOpioid dependenceOutcomeRetentionToxicologyTreatmentYoung adult

Identifiers

PMID24953168
PMCPMC4180514
OpenAlexW2164375280

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.