ArticleScientific reports2014
Three-dimensional super-resolution and localization of dense clusters of single molecules.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 48 citations in OpenAlex.
- Super-resolution microscopy based on the inherent fluctuations of dye molecules.Biomedical optics express · 2025Article
- Localizing axial dense emitters based on single-helix point spread function and compressed sensing.Nanophotonics (Berlin, Germany) · 2025Article
- Long-Axial-Range Double-Helix Point Spread Functions for 3D Volumetric Super-Resolution Imaging.The journal of physical chemistry. B · 2024Article
- Long axial-range double-helix point spread functions for 3D volumetric super-resolution imaging.bioRxiv : the preprint server for biology · 2024Article
- Investigating the Performances of Wide-Field Raman Microscopy with Stochastic Optical Reconstruction Post-Processing.Applied spectroscopy · 2022Article
- Recent advances in point spread function engineering and related computational microscopy approaches: from one viewpoint.Biophysical reviews · 2020Review
- Birefringent Fourier filtering for single molecule coordinate and height super-resolution imaging with dithering and orientation.Nature communications · 2020Article
- Light sheet approaches for improved precision in 3D localization-based super-resolution imaging in mammalian cells [Invited].Optics express · 2018Review
- Three-Dimensional Localization of Single Molecules for Super-Resolution Imaging and Single-Particle Tracking.Chemical reviews · 2017Review
- Extracting quantitative information from single-molecule super-resolution imaging data with LAMA - LocAlization Microscopy Analyzer.Scientific reports · 2016Article
- Generalized recovery algorithm for 3D super-resolution microscopy using rotating point spread functions.Scientific reports · 2016Article
- Novel approach for label free super-resolution imaging in far field.Scientific reports · 2015Article
- Far-field subwavelength imaging with near-field resonant metalens scanning at microwave frequencies.Scientific reports · 2015Article
- 3D multifocus astigmatism and compressed sensing (3D MACS) based superresolution reconstruction.Biomedical optics express · 2015Article
- 3D high-density localization microscopy using hybrid astigmatic/ biplane imaging and sparse image reconstruction.Biomedical optics express · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When a single molecule is detected in a wide-field microscope, the image approximates the point spread function of the system. However, as the distribution of molecules becomes denser and their images begin to overlap, existing solutions to determine the number of molecules present and their precise three-dimensional locations can tolerate little to no overlap. We propose a localization scheme that can identify several overlapping molecule images while maintaining high localization precision. A solution to this problem involving matched optical and digital techniques, as here proposed, can substantially increase the allowable labeling density and accelerate the data collection time of single-molecule localization microscopy by more than one order of magnitude.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.