Evidence map›Paper›PMID 24951810›Full record

ArticleJournal of clinical microbiology2014

Rothia bacteremia: a 10-year experience at Mayo Clinic, Rochester, Minnesota.

Poornima Ramanan, Jason N Barreto, Douglas R Osmon, Pritish K Tosh

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 1 synthesis or guideline pooled it, 172 citations in OpenAlex.

  1. The microbiota in eosinophilic esophagitis: A systematic review.Journal of gastroenterology and hepatology · 2022
    Pooled it
  2. Effects ofNutrients · 2020
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  6. First characterization of the oral microbiota of capybaras (Hydrochoerus hydrochaeris) in Brazil: insights into one health risks.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  10. Characteristics of the gut-lung axis in patients with viral pneumonia and respiratory failure.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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  12. Knee Septic Arthritis Caused by Coinfection withAntibiotics (Basel, Switzerland) · 2025
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  13. Seven genome sequences ofMicrobiology resource announcements · 2025
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  17. Oral Microbiome Changes During Hospitalization in Older Adults Not Receiving Mechanical Ventilation.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2025
    Observational
  18. A Rare Agent in Blood:Infectious diseases & clinical microbiology · 2025
    Article
  19. Human microbiome in post-acute COVID-19 syndrome (PACS).Current research in microbial sciences · 2025
    Article
  20. Review

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Poornima RamananDivision of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Jason N BarretoDepartment of Pharmacy, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Douglas R OsmonDivision of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Pritish K ToshDivision of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota, USA tosh.pritish@mayo.edu.
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rothia spp. are Gram-positive cocco-bacilli that cause a wide range of serious infections, especially in immunocompromised hosts. Risk factors for Rothia mucilaginosa (previously known as Stomatococcus mucilaginosus) bacteremia include prolonged and profound neutropenia, malignancy, and an indwelling vascular foreign body. Here, we describe 67 adults at the Mayo Clinic in Rochester, MN, from 2002 to 2012 with blood cultures positive for Rothia. Twenty-five of these patients had multiple positive blood cultures, indicating true clinical infection. Among these, 88% (22/25) were neutropenic, and 76% (19/25) had leukemia. Common sources of bacteremia were presumed gut translocation, mucositis, and catheter-related infection. One patient died with Rothia infection. Neutropenic patients were less likely to have a single positive blood culture than were nonneutropenic patients. Antimicrobial susceptibility testing was performed on 21% of the isolates. All of the tested isolates were susceptible to vancomycin and most beta-lactams; however, four of six tested isolates were resistant to oxacillin. There was no difference between the neutropenic and nonneutropenic patients in need of intensive care unit care, mortality, or attributable mortality.

Indexed as

AdultAgedAnti-Bacterial AgentsBacteremiaBloodCohort StudiesFemaleGram-Positive Bacterial InfectionsHumansLeukemiaMaleMicrobial Sensitivity TestsMicrococcaceaeMiddle AgedMinnesotaRetrospective StudiesAnti-Bacterial Agents

Identifiers

PMID24951810
PMCPMC4313135
OpenAlexW2023812968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.