Evidence map›Paper›PMID 24950841›Full record

Trial reportTrials2014

Efficacy of electroacupuncture for symptoms of menopausal transition: study protocol for a randomized controlled trial.

Zhishun Liu, Yang Wang, Huanfang Xu, Jiani Wu, Liyun He, John Yi Jiang, Shiyan Yan, Ruosang Du, Baoyan Liu

Registry-linked trialOpen access · goldAbstract readClinical Trial, Phase IIMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01849172 (Effect and Safety of Electroacupuncture for Symptoms of Menopausal Transition -a Multicenter Randomized Controlled Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01849172 nacompletednot on this map

Effect and Safety of Electroacupuncture for Symptoms of Menopausal Transition -a Multicenter Randomized Controlled Trial

TypeinterventionalSponsorGuang'anmen Hospital of China Academy of Chinese Medical SciencesRan2013 to 2016Enrolled360ConditionsMenopausal SyndromeArmselectroacupuncture, sham electroacupuncture
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zhishun Liu
Yang Wang
Huanfang Xu
Jiani Wu
Liyun He
John Yi Jiang
Shiyan Yan
Ruosang Du
Baoyan LiuGuang'anmen Hospital, China Academy of Chinese Medical Sciences, No,5, Beixiange Street, 100053 Beijing, Xicheng District, China. liuby@mail.cintcm.ac.cn.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNGuang’anmen Hospital · CNChina Academy of Chinese Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have shown that acupuncture can alleviate postmenopausal symptoms, such as hot flashes, but few studies have assessed symptoms during the menopausal transition (MT) period. Thus, the effect of acupuncture upon MT symptoms is unclear. We designed a large-scale trial aimed at evaluating the efficacy of electroacupuncture for MT symptoms compared with sham electroacupuncture and at observing the safety of electroacupuncture. METHODS/

designIn this multicenter randomized controlled trial, 360 women will be randomized to either an electroacupuncture group or a sham electroacupuncture group. During the 8-week-long treatment, a menopause rating scale, average 24-hour hot flash score, Menopause-Specific Quality of Life Questionnaire score, and level of female hormones will be observed. Follow-ups at the 20th and 32nd week will be made. DISCUSSION: Though there is no completely inert placebo acupuncture and blinding is difficult in acupuncture trials, the placebo effect of EA can still be partially excluded in this study. For the placebo control, we use non-points and a tailor-made sham needle. This needle is different from a retractable needle, which is usually used for sham acupuncture. The needle in this trial is more simply constructed and more acceptable to Chinese people. We expect to evaluate the efficacy of electroacupuncture for MT symptoms and clarify its effect on these symptoms.

trial registrationClinicalTrials.gov Identifier: NCT01849172 (Date of registration: 05/05/2013).

Indexed as

MenopauseAcupuncture PointsElectroacupunctureFemaleFollow-Up StudiesHot FlashesHumansMiddle AgedNeedlesPlacebo EffectProspective StudiesQuality of LifeResearch Design

Identifiers

PMID24950841
PMCPMC4075980
OpenAlexW2056429378

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.