Evidence map›Paper›PMID 24950600›Full record

ReviewTrends in neurosciences2014

From molecule to mind: an integrative perspective on odor intensity.

Joel D Mainland, Johan N Lundström, Johannes Reisert, Graeme Lowe

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Organoid models for chemosensing cell studies.American journal of physiology. Cell physiology · 2025
    Review
  6. Recalibrating Olfactory Neuroscience to the Range of Naturally Occurring Odor Concentrations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The human olfactory bulb processes odor valence representation and cues motor avoidance behavior.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joel D MainlandMonell Chemical Senses Center, Philadelphia, PA, USA; Department of Neuroscience, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: jmainland@monell.org.
Johan N LundströmMonell Chemical Senses Center, Philadelphia, PA, USA; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Johannes ReisertMonell Chemical Senses Center, Philadelphia, PA, USA.
Graeme LoweMonell Chemical Senses Center, Philadelphia, PA, USA.

Funding

DENDRITIC SIGNALING IN THE OLFACTORY BULBR01DC004208 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI LOWE, GRAEME · 2001 to 2012
$2.9M
Perceptual effects of genetic variation in human odorant receptorsR01DC013339 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI MAINLAND, JOEL D · 2013 to 2017
$1.9M
Dynamic Aspects of Olfactory Signal TransductionR01DC009613 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI REISERT, JOHANNES · 2010 to 2014
$1.5M
NIDCD NIH HHS DC009613NIDCD NIH HHS DC013339NIDCD NIH HHS DC04208NIDCD NIH HHS R01 DC004208NIDCD NIH HHS R01 DC009613NIDCD NIH HHS R01 DC013339
6 · The paper itself

Abstract

A fundamental problem in systems neuroscience is mapping the physical properties of a stimulus to perceptual characteristics. In vision, wavelength translates into color; in audition, frequency translates into pitch. Although odorant concentration is a key feature of olfactory stimuli, we do not know how concentration is translated into perceived intensity by the olfactory system. A variety of neural responses at several levels of processing have been reported to vary with odorant concentration, suggesting specific coding models. However, it remains unclear which, if any, of these phenomena underlie the perception of odor intensity. Here, we provide an overview of current models at different stages of olfactory processing, and identify promising avenues for future research.

Indexed as

OdorantsAnimalsHumansOlfactory PathwaysOlfactory PerceptionSensory Receptor CellsSmell

Identifiers

PMID24950600
PMCPMC4119848

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.