ArticleEnvironment international2014
Health effects of multi-pollutant profiles.
Article in Environment international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Particulate metal exposures induce plasma metabolome changes in a commuter panel study.PloS one · 2018Trial
- Combined Effect of Metals, PFAS, Phthalates, and Plasticizers on Cardiovascular Disease Risk.Toxics · 2025Article
- Metabolomics Signatures of Exposure to Ambient Air Pollution: A Large-Scale Metabolome-Wide Association Study in the Cancer Prevention Study-II Nutrition Cohort.Environmental science & technology · 2025Article
- Disentangling impacts of multiple pollutants on acute cardiovascular events in New York city: A case-crossover analysis.Environmental research · 2024Article
- Exposure to Cadmium, Lead, Mercury, and Arsenic and Uric Acid Levels: Results from NHANES 2007-2016.Biological trace element research · 2023Article
- Predictive modeling and analysis of air quality - Visualizing before and during COVID-19 scenarios.Journal of environmental management · 2023Article
- KERNEL MACHINE AND DISTRIBUTED LAG MODELS FOR ASSESSING WINDOWS OF SUSCEPTIBILITY TO ENVIRONMENTAL MIXTURES IN CHILDREN'S HEALTH STUDIES.The annals of applied statistics · 2022Article
- Exploring associations between prenatal exposure to multiple endocrine disruptors and birth weight with exposure continuum mapping.Environmental research · 2021Article
- Air Pollution, Neonatal Immune Responses, and Potential Joint Effects of Maternal Depression.International journal of environmental research and public health · 2021Article
- Multiple air pollutant exposure and lung cancer in Tehran, Iran.Scientific reports · 2021Article
- Model choice for estimating the association between exposure to chemical mixtures and health outcomes: A simulation study.PloS one · 2021Article
- Using Latent Class Modeling to Jointly Characterize Economic Stress and Multipollutant Exposure.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- [Combined effects of different environmental factors on health: air pollution, temperature, green spaces, pollen, and noise].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2020Review
- Exposure to urban particulate matter and its association with human health risks.Environmental science and pollution research international · 2020Review
- Probabilistic predictive principal component analysis for spatially misaligned and high-dimensional air pollution data with missing observations.Environmetrics · 2020Article
- Model-averaged confounder adjustment for estimating multivariate exposure effects with linear regression.Biometrics · 2018Article
- Environmental exposure mixtures: questions and methods to address them.Current epidemiology reports · 2018Article
- Multi-pollutant Modeling Through Examination of Susceptible Subpopulations Using Profile Regression.Current environmental health reports · 2018Review
- The Joint Effect of Prenatal Exposure to Metal Mixtures on Neurodevelopmental Outcomes at 20-40 Months of Age: Evidence from Rural Bangladesh.Environmental health perspectives · 2017Article
- Association between Pesticide Profiles Used on Agricultural Fields near Maternal Residences during Pregnancy and IQ at Age 7 Years.International journal of environmental research and public health · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe association between exposure to particle mass and mortality is well established; however, there are still uncertainties as to whether certain chemical components are more harmful than others. Moreover, understanding the health effects associated with exposure to pollutant mixtures may lead to new regulatory strategies.
objectivesRecently we have introduced a new approach that uses cluster analysis to identify distinct air pollutant mixtures by classifying days into groups based on their pollutant concentration profiles. In Boston during the years 1999-2009, we examined whether the effect of PM2.5 on total mortality differed by distinct pollution mixtures.
methodsWe applied a time series analysis to examine the association of PM2.5 with daily deaths. Subsequently, we included an interaction term between PM2.5 and the pollution mixture clusters.
resultsWe found a 1.1% increase (95% CI: 0.0, 2.2) and 2.3% increase (95% CI: 0.9-3.7) in total mortality for a 10 μg/m(3) increase in the same day and the two-day average of PM2.5 respectively. The association is larger in a cluster characterized by high concentrations of the elements related to primary traffic pollution and oil combustion emissions with a 3.7% increase (95% CI: 0.4, 7.1) in total mortality, per 10 μg/m(3) increase in the same day average of PM2.5.
conclusionsOur study shows a higher association of PM2.5 on total mortality during days with a strong contribution of traffic emissions, and fuel oil combustion. Our proposed method to create multi-pollutant profiles is robust, and provides a promising tool to identify multi-pollutant mixtures which can be linked to the health effects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.