ArticleBioMed research international2014
Propolis varnish: antimicrobial properties against cariogenic bacteria, cytotoxicity, and sustained-release profile.
Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Evaluation of the Remineralisation and Antibacterial Properties of Propolis, Chitosan, and Theobromine.Oral health & preventive dentistry · 2026Article
- Antibacterial activity, cytotoxicity, and microshear bond strength of an experimental adhesive system containing chitosan-based silver oxide particles.Odontology · 2026Article
- Antibacterial, Antibiofilm, and Tooth Color Preservation Capacity of Magnesium Oxide Nanoparticles Varnish (in vitro Study).Nanotechnology, science and applications · 2024Article
- Efficacy of a 0.5% Propolis -0.9% Pomegranate Buccal Spray Treatment Compared with 2% Miconazole Gel for Denture Stomatitis Treatment in Elderly Patients: a Randomized Clinical Trial.Journal of dentistry (Shiraz, Iran) · 2022Article
- Potential Combinatory Effect of Cannabidiol and Triclosan Incorporated into Sustained Release Delivery System against Oral Candidiasis.Pharmaceutics · 2022Article
- Effect of Propolis Paste and Mouthwash Formulation on Healing after Teeth Extraction in Periodontal Disease.Plants (Basel, Switzerland) · 2021Article
- Antimicrobial Efficacy of Propolis-Containing Varnish in Children: A Randomized and Double-Blind Clinical Trial.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Propolis in Oral Healthcare: Antibacterial Activity of a Composite Resin Enriched With Brazilian Red Propolis.Frontiers in pharmacology · 2021Article
- Chemical composition and antimycoplasma activity of a brown propolis from southern Brazil.Journal of food science and technology · 2020Article
- Evidence-Based Studies and Perspectives of the Use of Brazilian Green and Red Propolis in Dentistry.European journal of dentistry · 2019Article
- Anti-biofilm and remineralization effects of chitosan hydrogel containing amelogenin-derived peptide on initial caries lesions.Regenerative biomaterials · 2018Article
- The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures.Molecules (Basel, Switzerland) · 2017Article
- Antibacterial activity againstJournal of advanced research · 2017Article
- Role of Herbal Agents - Tea Tree Oil andJournal of clinical and diagnostic research : JCDR · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Varnishes are preparations that differ in the polymeric matrix and therapeutical agents. In dentistry they are used to prevent caries. In this study we developed a propolis varnish, considering propolis properties against cariogenic bacteria. To a chitosan polymeric base (CHV) was added ethanolic propolis extract in different concentrations: PV1 (5%), PV2 (10%), and PV3 (15%). Antimicrobial activity was carried out against Streptococcus mutans (SM), Streptococcus sanguinis (SG), Streptococcus salivarius (SS), and Lactobacillus casei (LC) through agar diffusion method. The three propolis concentrations incorporated were effective in inhibiting the growth of all microorganisms, but without significant difference between the zones of inhibition observed. Cytotoxicity assay was done by MTT method. Data were analyzed by one-way ANOVA and Bonferroni test. None of the varnishes were cytotoxic, keeping 80% of viable cells, while CHV allowed cellular proliferation (120%). Sustained-release test was carried out by applying 40 μ L of each varnish in the buccal surface of bovine teeth and kept in an ethanol/water solution removed in regular times. According to the "independent model approach," the release profiles were distinct from each varnish and the most prolonged was PV3 (8 weeks). Varnish formulations had satisfactory antimicrobial activity against cariogenic bacteria and have a low cytotoxicity (<50%).
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Registered trials
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