Evidence map›Paper›PMID 24949344›Full record

ArticleEndoscopic ultrasound2012

Effect of Povidone-iodine Washing of Gastrointestinal Mucosa or Taking Proton Pump Inhibitors on Bacteremia after Endoscopic Ultrasonography-guided Fine Needle Aspiration.

Na Li, Hongmin Qi, Zhijun Liu, Nan Ge, Jintao Guo, Guoxin Wang, Xiang Liu, Sheng Wang, Siyu Sun

Open access · hybridAbstract read
In one paragraph

Article in Endoscopic ultrasound, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Na LiHospice Ward, Shengjing Hospital of China Medical University, Shenyang, China.
Hongmin QiEndoscopy Center, People's Hospital of Liaoning Province, Shenyang, China.
Zhijun LiuEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
Nan GeEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
Jintao GuoEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
Guoxin WangEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
Xiang LiuEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
Sheng WangEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
Siyu SunEndoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFew studies have evaluated the risk of bacteremia and infectious complications after endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA). Therefore, we aimed to study the frequency of bacteremia and search for a method to potentially reduce bacterial infection after EUS-FNA. We also investigated the effect of taking proton pump inhibitors (PPIs) before examination on the occurrence of bacteremia.

methodsA total of 28 healthy adult dogs were randomly assigned into three groups: control group, povidone-iodine group and omeprazole group. The dogs in the povidone-iodine group were administered with 0.5% povidone-iodine solution (10 mL) to wash gastrointestinal mucosa, while the dogs in the omeprazole group were fed with 20 mg omeprazole orally twice a day for 3 days before the EUS-FNA procedure. Blood samples were collected for cultures before EUS examination, between EUS and FNA, and 5 min, 15 min and 30 min after FNA.

resultsThere were 3 true-positive cases of bacteremia in the control group while there was 1 true-positive case of bacteremia in each of the two experiment groups. The differences in the occurrences of bacteremia between the control group and both experiment groups were not statistically significant.

conclusionThere are no statistically significant differences in the frequencies of bacteremia between the two experiment groups and the control group. Therefore, washing of the gastrointestinal mucosa with 0.5% povidone-iodine solution may not reduce the risk of bacterial infection and taking the PPIs does not increase the risk of bacteremia after EUS-FNA.

Indexed as

bacteremiablood cultureendoscopic ultrasonographyfine needle aspirationpovidone-iodine solutionproton pump inhibitor

Identifiers

PMID24949344
PMCPMC4062215
OpenAlexW2079391853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.