ArticlePakistan journal of medical sciences2014
Postoperative nosocomial infections among children with congenital heart disease.
Article in Pakistan journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Risk Factors and Microbiological Characterization of Healthcare Associated Infection Post Cardiac Surgery Among Children in Beijing, China.Infection and drug resistance · 2026Article
- Prevention of Respiratory Infections in Children with Congenital Heart Disease: Current Evidence and Clinical Strategies.Vaccines · 2025Review
- Analysis of healthcare-associated infection in patients with pulmonary arterial hypertension associated with congenital heart disease in PICU: Evidence from a tertiary hospital in western China.Frontiers in pediatrics · 2022Article
- Causes of Death in Infants and Children with Congenital Heart Disease.Pediatric cardiology · 2021Article
- Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease.BMC infectious diseases · 2020Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
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Abstract
objectiveTo study the pathogen distribution, antimicrobial susceptibility and risk factors of postoperative nosocomial infections among children with congenital heart disease.
methodsThree hundreds children with congenital heart disease admitted to our hospital to receive surgeries from February 2010 to February 2013 were selected.
resultsA total of 120 children were tested as positive by sputum culture, with the infection rate of 40.0%. The top five most common pathogenic microorganisms included Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus, Pseudomonas aeruginosa, and Candida albicans. S. epidermidis, S. aureus and Enterococcus were highly resistant to penicillin, azithromycin and erythromycin, moderately susceptible to levofloxacin and cefazolin, and completely susceptible to vancomycin. Multivariate Logistic regression analysis showed that hospitalization stay length, combined use of antibiotics, systemic use of hormones, mechanical ventilation and catheter indwelling were the independent risk factors of postoperative nosocomial infections (P<0.05).
conclusionNosocomial infection, which was the most frequent postoperative complication of pediatric congenital heart disease, was predominantly induced by Gram-positive bacteria that were highly susceptible to cephalosporins and vancomycin. Particular attention should be paid to decrease relevant risk factors to improve the prognosis.
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