ArticleClinical medicine insights. Case reports2014
Systemic Lupus Erythematosus (SLE) Complicated by Neuromyelitis Optica (NMO - Devic's Disease): Clinic-Pathological Report and Review of the Literature.
Article in Clinical medicine insights. Case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Contribution of germline and somatic mutations to risk of neuromyelitis optica spectrum disorder.Cell genomics · 2025Pooled it
- A Chinese child with both systemic lupus erythematosus coexisting with neuromyelitis optica spectrum disorder: a case report.Pediatric rheumatology online journal · 2024Article
- A rare case of systemic lupus erythematosus-associated neuromyelitis optica spectrum disorder with cystic lesions and dual seropositivity for anti-AQP4 and anti-MOG antibodies.Clinical case reports · 2024Article
- A new perspective on therapies involving B-cell depletion in autoimmune diseases.Molecular biology reports · 2024Article
- Nationwide analysis of neuromyelitis optica in systemic lupus erythematosus and Sjogren's syndrome.Clinical rheumatology · 2024Article
- Systemic Lupus Erythematous and Neuromyelitis Optica Causing Hypercapnic Respiratory Failure.The American journal of case reports · 2022Article
- Clinical Characteristics and Outcomes of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder With Brainstem Lesions as Heralding Prodrome.Frontiers in neurology · 2022Article
- The causal relationship between neuromyelitis optica spectrum disorder and other autoimmune diseases.Frontiers in immunology · 2022Article
- Neuromyelitis optica spectrum disorders and pregnancy: therapeutic considerations.Nature reviews. Neurology · 2020Review
- Article
- Association of severe and therapy-refractory systemic lupus erythematosus and neuromyelitis optica: a management challenge.BMJ case reports · 2018Article
- Features of anti-aquaporin 4 antibody-seropositive Chinese patients with neuromyelitis optica spectrum optic neuritis.Journal of neurology · 2015Article
- Differences in disease burden between neuromyelitis optica spectrum disorder and multiple sclerosis in South China.Multiple sclerosis journal - experimental, translational and clinicalArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuromyelitis optica (NMO) is usually a relapsing demyelinating disease of the central nervous system associated with optic neuritis, transverse myelitis involving three or more contiguous spinal cord segments, and seropositivity for NMO-IgG antibody. NMO is often mistaken for multiple sclerosis and there are relatively sporadic publications about NMO and overlapping systemic or organ-specific autoimmune diseases, such as systemic lupus erythematosus (SLE). We described a unique case of a 25-year-old Arab young woman who was diagnosed with SLE, depending on clinical, laboratory investigations and after she had fulfilled the diagnostic criteria for SLE and had presented the following findings: constitutional findings (fatigue, fever, and arthralgia); dermatologic finding (photosensitivity and butterfly rash); chronic renal failure (proteinuria up to 400 mg in 24 hours); hematologic and antinuclear antibodies (positivity for antinuclear factor (ANF), anti-double-stranded DNA antibodies, direct Coombs, ANA and anti-DNA, low C4 and C3, aCL by IgG and IgM). Recently, she presented with several episodes of transverse myelitis and optic neuritis. Clinical, radiological, and laboratory findings especially seropositivity for NMO-IgG were compatible with NMO. Accurate diagnosis is critical to facilitate initiation of immunosuppressive therapy for attack prevention. This case illustrates that NMO may be associated with SLE.
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