Evidence map›Paper›PMID 24948752›Full record

ArticleBMJ open2014

Analgesic use, pain and daytime sedation in people with and without dementia in aged care facilities: a cross-sectional, multisite, epidemiological study protocol.

Edwin C K Tan, Renuka Visvanathan, Sarah N Hilmer, Agnes I Vitry, Tara Quirke, Tina Emery, Leonie Robson, Terry Shortt, Simon Sheldrick, Sunny Soon Won Lee and 5 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Edwin C K TanFaculty of Pharmacy and Pharmaceutical Sciences, Centre for Medicine Use and Safety, Monash University, Melbourne, Australia.
Renuka VisvanathanDiscipline of Medicine, University of Adelaide, Adelaide, Australia Aged and Extended Care Services, The Queen Elizabeth Hospital and Adelaide Geriatrics Training and Research with Aged Care (GTRAC) Centre, School of Medicine, University of Adelaide, Adelaide, Australia.
Sarah N HilmerDepartments of Clinical Pharmacology and Aged Care, Kolling Institute of Medical Research, Sydney Medical School, Royal North Shore Hospital, The University of Sydney, Sydney, Australia Cognitive Decline Partnership Centre, Hornsby Ku-ring-gai Hospital, Hornsby, Australia.
Agnes I VitrySansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia.
Tara QuirkeConsumer Dementia Research Network, Alzheimer's Australia, Scullin, Australia.
Tina EmeryResthaven Limited, Adelaide, South Australia.
Leonie RobsonResthaven Limited, Adelaide, South Australia.
Terry ShorttResthaven Limited, Adelaide, South Australia.
Simon SheldrickResthaven Limited, Adelaide, South Australia.
Sunny Soon Won LeeResthaven Limited, Adelaide, South Australia.
Robyn ClothierAged and Extended Care Services, The Queen Elizabeth Hospital and Adelaide Geriatrics Training and Research with Aged Care (GTRAC) Centre, School of Medicine, University of Adelaide, Adelaide, Australia Resthaven Limited, Adelaide, South Australia.
Emily ReeveDepartments of Clinical Pharmacology and Aged Care, Kolling Institute of Medical Research, Sydney Medical School, Royal North Shore Hospital, The University of Sydney, Sydney, Australia Cognitive Decline Partnership Centre, Hornsby Ku-ring-gai Hospital, Hornsby, Australia.
Danijela GnjidicDepartments of Clinical Pharmacology and Aged Care, Kolling Institute of Medical Research, Sydney Medical School, Royal North Shore Hospital, The University of Sydney, Sydney, Australia Faculty of Pharmacy, University of Sydney, Sydney, Australia.
Jenni IlomäkiFaculty of Pharmacy and Pharmaceutical Sciences, Centre for Medicine Use and Safety, Monash University, Melbourne, Australia.
J Simon BellFaculty of Pharmacy and Pharmaceutical Sciences, Centre for Medicine Use and Safety, Monash University, Melbourne, Australia Cognitive Decline Partnership Centre, Hornsby Ku-ring-gai Hospital, Hornsby, Australia Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia Kuopio Research Centre of Geriatric Care, University of Eastern Finland, Kuopio, Finland.
Resthaven Incorporated · AUMonash University · AURoyal North Shore Hospital · AUQueen Elizabeth Hospital · AUDementia Australia · AUUniversity of South Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeople living with dementia may experience and express pain in different ways to people without dementia. People with dementia are typically prescribed fewer analgesics than people without dementia indicating a potential difference in how pain is identified and treated in these populations. The objectives of this study are to (1) investigate the prevalence of analgesic load, pain and daytime sedation in people with and without dementia in Australian residential aged care facilities (RACFs), and (2) investigate the clinical and diagnostic associations between analgesic load, pain and daytime sedation in people with and without dementia in Australian RACFs. METHODS/ANALYSIS: This will be a cross-sectional study of 300 permanent residents of up to 10 low-level and high-level RACFs in South Australia with and without dementia. Trained study nurses will administer validated and dementia-specific assessments of self-reported and clinician-observed pain, sedation and other clinical and humanistic outcomes. Medicine-use data will be extracted directly from each resident's medication administration chart. Binary and multinominal logistic regression will be used to compute unadjusted and adjusted ORs and 95% CIs for factors associated with pain, analgesic load and daytime sedation. These factors will include dementia severity, behavioural and psychological symptoms, quality of life, resident satisfaction, attitudes towards medicines, activities of daily living and nutritional status. ETHICS AND DISSEMINATION: Institutional ethics approval has been granted. The findings will be disseminated through public lectures, professional and scientific conferences and in peer-reviewed journal articles. The findings of this study will allow for a better understanding of the prevalence and factors associated with analgesic use, pain and other outcomes in residential care. The findings of this study will be used to inform the development and implementation of strategies to improve the quality of life of people with dementia.

Indexed as

AgedAnalgesicsCross-Sectional StudiesDementiaHomes for the AgedHumansHypnotics and SedativesPainPain ManagementResearch DesignAnalgesicsHypnotics and SedativesEpidemiologyGeriatric MedicinePain Management

Identifiers

PMID24948752
PMCPMC4067818
OpenAlexW2148766446

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.