Trial reportThe Journal of pediatrics2014
Relationships among stressful life events and physiological markers, treatment adherence, and psychosocial functioning among youth with type 2 diabetes.
Trial report in The Journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT00081328. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Studies to Treat Or Prevent Pediatric Type 2 Diabetes (STOPP-T2D) Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Clinical Trial
Who cites it
40 citing papers in PubMed, 58 citations in OpenAlex.
- Trial
- Psychosocial and Behavioral Correlates of A1C and Quality of Life Among Young Adults With Diabetes.The Diabetes educator · 2018Trial
- Resilient, Empowered, Active Living with Diabetes (REAL Diabetes) study: Methodology and baseline characteristics of a randomized controlled trial evaluating an occupation-based diabetes management intervention for young adults.Contemporary clinical trials · 2017Trial
- Understanding Community-Specific Health Behaviors to Prevent Type 2 Diabetes and Depression in Rural Adolescents: A Qualitative Study.International journal of behavioral medicine · 2026Article
- Treatment of Youth-Onset Type 2 Diabetes: Focus on SGLT-2 Inhibitor Use.Pediatric diabetes · 2026Review
- Youth-Onset Type 2 Diabetes: What We've Learned From Key Youth-Onset Type 2 Diabetes Studies, What We Still Don't Know, and Why It Is Important.Diabetes care · 2025Review
- Child Opportunity Index: Does It Foretell Future Glycemic Control and Health Care Utilization in Youth With Type 1 or Type 2 Diabetes?Clinical diabetes : a publication of the American Diabetes Association · 2025Article
- The impact of type 2 diabetes on adolescent and family functioning and healthcare use: findings from the National Survey of Children's Health.Frontiers in endocrinology · 2025Article
- Pathophysiology and Treatment of Prediabetes and Type 2 Diabetes in Youth.Diabetes care · 2024Review
- Increases in Psychological Stress Are Associated With Higher Fasting Glucose in US Chinese Immigrants.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024Article
- Historical trauma and oppression: Associations with internalizing outcomes among American Indian adults with type 2 diabetes.Transcultural psychiatry · 2024Article
- Stressors and coping strategies among secondary school male students in Abha City, Saudi Arabia.Frontiers in psychology · 2024Article
- Reassessing type 2 diabetes in adolescents and its management strategies based on insulin resistance.Frontiers in endocrinology · 2024Review
- Visfatin and Retinol Binding Protein-4 in Young-Onset Type 2 Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2023Article
- Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023Article
- Youth-Onset Type 2 Diabetes: Burden of Complications and Socioeconomic Cost.Current diabetes reports · 2023Review
- Adolescents with Type 2 Diabetes: Overcoming Barriers to Effective Weight Management.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Review
- Text Messages and Financial Incentives to Increase Physical Activity in Adolescents With Prediabetes and Type 2 Diabetes: Web-Based Group Interviews to Inform Intervention Design.JMIR diabetes · 2022Article
- Equity in Psychosocial Outcomes and Care for Racial and Ethnic Minorities and Socioeconomically Disadvantaged People With Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2022Article
- Getting Active Mindfully: Rationale and Case Illustration of a Group Mind-body and Activity Program for Chronic Pain.Journal of clinical psychology in medical settings · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 9 institutions in 1 country.
Funding
Abstract
objectiveTo examine the relationships between stressful life events and physiological measures, adherence to prescribed oral medication regimens, depressive symptoms, and impaired quality of life (QoL) in adolescents with recent-onset type 2 diabetes (T2D). STUDY
designData were collected from 497 ethnically diverse participants (66% female) in the final year of the Treatment Options for Type 2 Diabetes in Adolescents and Youth multicenter clinical trial. Exposure to 32 possible events over the previous year and rating of subsequent distress were collected by self-report and summarized as a major stressors score. This score was analyzed for relationship to glycemic control (hemoglobin A1c and treatment failure), body mass index, diagnosis of hypertension or triglyceride dyslipidemia, adherence to a prescribed oral medication regimen, presence of depressive symptoms, and impaired QoL.
resultsThe total number of major stressful life events in the adolescents with T2D was calculated, with 33% reporting none, 67% reporting ≥ 1, 47% reporting ≥ 2, 33% reporting ≥ 3, and 20% reporting ≥ 4. There were no associations between the major stressors score and physiological measures or diagnosis of comorbidities. The odds of medication nonadherence increased significantly from those reporting ≥ 1 major stressor (OR, 1.58; P = .0265) to those reporting ≥ 4 major stressors (OR, 2.70; P = .0009). Significant odds of elevated depressive symptoms and impaired QoL were also found with increased reporting of major stressors.
conclusionExposure to major stressful life events is associated with lower adherence to prescribed oral medication regimens and impaired psychosocial functioning in adolescents with T2D.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.