ArticleThe Plant journal : for cell and molecular biology2014
The low-recombining pericentromeric region of barley restricts gene diversity and evolution but not gene expression.
Article in The Plant journal : for cell and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres.Nature plants · 2026Article
- Crossovers break new ground.Nature plants · 2026Article
- Characterising the Genomic Landscape of Differentiation Between Annual and Perennial Rye.Evolutionary applications · 2024Article
- QTL Analysis of β-Glucan Content and Other Grain Traits in a Recombinant Population of Spring Barley.International journal of molecular sciences · 2024Article
- The chromatin determinants and Ph1 gene effect at wheat sites with contrasting recombination frequency.Journal of advanced research · 2023Article
- Major chromosome 5H haplotype switch structures the European two-rowed spring barley germplasm of the past 190 years.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- The evolutionary patterns of barley pericentromeric chromosome regions, as shaped by linkage disequilibrium and domestication.The Plant journal : for cell and molecular biology · 2022Article
- Recombination landscape divergence between populations is marked by larger low-recombining regions in domesticated rye.Molecular biology and evolution · 2022Article
- Genomic prediction of the recombination rate variation in barley - A route to highly recombinogenic genotypes.Plant biotechnology journal · 2022Article
- Article
- Discovery of a novel powdery mildew (Blumeria graminis) resistance locus in rye (Secale cereale L.).Scientific reports · 2021Article
- The draft genome of a wild barley genotype reveals its enrichment in genes related to biotic and abiotic stresses compared to cultivated barley.Plant biotechnology journal · 2020Article
- Article
- Genome-wide association mapping in a diverse spring barley collection reveals the presence of QTL hotspots and candidate genes for root and shoot architecture traits at seedling stage.BMC plant biology · 2019Article
- desynaptic5 carries a spontaneous semi-dominant mutation affecting Disrupted Meiotic cDNA 1 in barley.Journal of experimental botany · 2019Article
- A pan-transcriptome analysis shows that disease resistance genes have undergone more selection pressure during barley domestication.BMC genomics · 2019Article
- New Possibilities on the Horizon: Genome Editing Makes the Whole Genome Accessible for Changes.Frontiers in plant science · 2019Review
- The Evolutionary Consequences of Transposon-Related Pericentromer Expansion in Melon.Genome biology and evolution · 2018Article
- Genome-Wide Association Analysis of Grain Yield-Associated Traits in a Pan-European Barley Cultivar Collection.The plant genome · 2018Article
- Sequencing of Single Pollen Nuclei Reveals Meiotic Recombination Events at Megabase Resolution and Circumvents Segregation Distortion Caused by Postmeiotic Processes.Frontiers in plant science · 2017Article
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16 authors.
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Abstract
The low-recombining pericentromeric region of the barley genome contains roughly a quarter of the genes of the species, embedded in low-recombining DNA that is rich in repeats and repressive chromatin signatures. We have investigated the effects of pericentromeric region residency upon the expression, diversity and evolution of these genes. We observe no significant difference in average transcript level or developmental RNA specificity between the barley pericentromeric region and the rest of the genome. In contrast, all of the evolutionary parameters studied here show evidence of compromised gene evolution in this region. First, genes within the pericentromeric region of wild barley show reduced diversity and significantly weakened purifying selection compared with the rest of the genome. Second, gene duplicates (ohnolog pairs) derived from the cereal whole-genome duplication event ca. 60MYa have been completely eliminated from the barley pericentromeric region. Third, local gene duplication in the pericentromeric region is reduced by 29% relative to the rest of the genome. Thus, the pericentromeric region of barley is a permissive environment for gene expression but has restricted gene evolution in a sizeable fraction of barley's genes.
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