ArticleExpert review of vaccines2014
The importance of B cell CD1d expression for humoral immunity.
Article in Expert review of vaccines, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- B cell-expressed CD1d promotes MPL/TDCM lipid emulsion adjuvant effects in polysaccharide vaccines.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Liposomes Bearing Non-Bilayer Phospholipid Arrangements Induce Specific IgG Anti-Lipid Antibodies by Activating NK1.1Membranes · 2022Article
- Use of aFrontiers in immunology · 2021Article
- Activation of Human CD11bFrontiers in immunology · 2018Observational
- Coordination between T helper cells, iNKT cells, and their follicular helper subsets in the humoral immune response against Clostridium difficile toxin B.Journal of leukocyte biology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
It was reported over a decade previously that CD1d-restricted Natural Killer T (NKT) cells could interact with CD1d-expressing B cells and facilitate antibody secretion. Since then, several studies have observed that NKT cells can provide B-cell help for production of antibody against model and pathogen-derived glycolipids, carbohydrates and proteins. In regard to T cell-dependent protein antigens, it is still not entirely clear to what extent cognate interactions between CD1d-expressing B cells and NKT cells contribute to initial and long-lived B-cell responses that are characteristic of such antigens. In this editorial, we review evidence that NKT cells provide CD1d-dependent cognate and non-cognate forms of B-cell help following immunization with protein antigen. Elucidating these mechanisms will be important for harnessing NKT cells during vaccination.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.