ArticleScientific reports2014
Analysis of phytoplasma-responsive sRNAs provide insight into the pathogenic mechanisms of mulberry yellow dwarf disease.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 41 citations in OpenAlex.
- Phytoplasma-plant interactions: effector-mediated host reprogramming, hormonal crosstalk, metabolic alterations and plant-mediated vector manipulation.World journal of microbiology & biotechnology · 2026Review
- Integrated Analysis of lncRNAs and mRNAs Reveals Complex Gene Network Mediated by lncRNAs and Regulatory Function ofBiomolecules · 2024Article
- Genome-Wide Comprehensive Identification andGenetics research · 2024Article
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- The miR393-Target Module Regulates Plant Development and Responses to Biotic and Abiotic Stresses.International journal of molecular sciences · 2022Review
- Plant Hormones in Phytoplasma Infected Plants.Frontiers in plant science · 2019Review
- Alterations of plant architecture and phase transition by the phytoplasma virulence factor SAP11.Journal of experimental botany · 2018Article
- Integrated Phloem Sap mRNA and Protein Expression Analysis Reveals Phytoplasma-infection Responses in Mulberry.Molecular & cellular proteomics : MCP · 2018Article
- ceRNA Cross-Talk in Paulownia Witches' Broom Disease.International journal of molecular sciences · 2018Article
- Plant Responses to Pathogen Attack: Small RNAs in Focus.International journal of molecular sciences · 2018Review
- MiRNA-seq-based profiles of miRNAs in mulberry phloem sap provide insight into the pathogenic mechanisms of mulberry yellow dwarf disease.Scientific reports · 2018Article
- miRVIT: A Novel miRNA Database and Its Application to UncoverFrontiers in plant science · 2018Article
- Plant Small Non-coding RNAs and Their Roles in Biotic Stresses.Frontiers in plant science · 2018Review
- Article
- A Novel LncRNA,Frontiers in plant science · 2018Article
- Genetic diversity among mulberry genotypes from seven countries.Physiology and molecular biology of plants : an international journal of functional plant biology · 2017Article
- Characterization of microRNAs of Beta macrocarpa and their responses to Beet necrotic yellow vein virus infection.PloS one · 2017Article
- Comparative Proteomic Analysis ofInternational journal of genomics · 2017Article
- Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The yellow dwarf disease associated with phytoplasmas is one of the most devastating diseases of mulberry and the pathogenesis involved in the disease is poorly understood. To analyze the molecular mechanisms mediating gene expression in mulberry-phytoplasma interaction, the comprehensive sRNA changes of mulberry leaf in response to phytoplasma-infection were examined. A total of 164 conserved miRNAs and 23 novel miRNAs were identified, and 62 conserved miRNAs and 13 novel miRNAs were found to be involved in the response to phytoplasma-infection. Meanwhile, target genes of the responsive miRNAs were identified by sequencing of the degradome library. In addition, the endogenous siRNAs were sequenced, and their expression profiles were characterized. Interestingly, we found that phytoplasma infection induced the accumulation of mul-miR393-5p which was resulted from the increased transcription of MulMIR393A, and mul-miR393-5p most likely initiate the biogenesis of siRNAs from TIR1 transcript. Based on the results, we can conclude that phytoplasma-responsive sRNAs modulate multiple hormone pathways and play crucial roles in the regulation of development and metabolism. These responsive sRNAs may work cooperatively in the response to phytoplasma-infection and be responsible for some symptoms in the infected plants.
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