ArticleGenetics in medicine : official journal of the American College of Medical Genetics2015
Characteristics associated with genetic counseling referral and BRCA1/2 testing among women in a large integrated health system.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Pretest Video Education Versus Genetic Counseling for Patients With Prostate Cancer: ProGen, A Multisite Randomized Controlled Trial.JCO oncology practice · 2023Trial
- Provider effects and racial inequities in breast cancer risk-management adoption: Findings from a community-based study of high-risk women.Patient education and counseling · 2026Article
- Improving genetics equity: identifying women eligible for genetic care services using mammography clinics in underserved areas as screening hubs.The oncologist · 2025Article
- Implementation of BRCA Test among Young Breast Cancer Patients in South Korea: A Nationwide Cohort Study.Cancer research and treatment · 2024Article
- Risk-management decision-making data from a community-based sample of racially diverse women at high risk of breast cancer: rationale, methods, and sample characteristics of the Daughter Sister Mother Project survey.Breast cancer research : BCR · 2024Article
- Article
- Residential Locale Is Associated with Disparities in Genetic Testing-Related Outcomes Among BRCA1/2-Positive Women.Journal of racial and ethnic health disparities · 2023Article
- An Accessible Communication System for Population-Based Genetic Testing: Development and Usability Study.JMIR formative research · 2022Article
- Primary care physician referral practices regarding BRCA1/2 genetic counseling in a major health system.Breast cancer research and treatment · 2022Article
- Prevalence of Americans reporting a family history of cancer indicative of increased cancer risk: Estimates from the 2015 National Health Interview Survey.Preventive medicine · 2022Article
- Recommendation and Acceptance of Counselling for Familial Cancer Risk in Newly Diagnosed Breast Cancer Cases.Breast care (Basel, Switzerland) · 2022Article
- "Being proactive, not reactive": exploring perceptions of genetic testing among White, Latinx, and Pacific Islander Populations.Journal of community genetics · 2021Article
- Genetic Testing May Help Reduce Breast Cancer Disparities for African American Women.Journal of the National Cancer Institute · 2020Article
- Mainstreamed genetic testing of breast cancer patients in two hospitals in South Eastern Norway.Familial cancer · 2020Article
- Socio-culturally mediated factors and lower level of education are the main influencers of functional cervical cancer literacy among women in Mayuge, Eastern Uganda.Ecancermedicalscience · 2020Article
- Trends in BRCA Test Utilization in an Integrated Health System, 2005-2015.Journal of the National Cancer Institute · 2019Article
- Persistent Underutilization of BRCA1/2 Testing Suggest the Need for New Approaches to Genetic Testing Delivery.Journal of the National Cancer Institute · 2019Article
- Racial/Ethnic Disparities in BRCA Counseling and Testing: a Narrative Review.Journal of racial and ethnic health disparities · 2019Review
- Evaluation of Cancer-Based Criteria for Use in Mainstream BRCA1 and BRCA2 Genetic Testing in Patients With Breast Cancer.JAMA network open · 2019Article
- Evaluating and improving the implementation of a community-based hereditary cancer screening program.Journal of community genetics · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundEvidence shows underutilization of cancer genetics services. To explore the reasons behind this underutilization, this study evaluated characteristics of women who were referred for genetic counseling and/or had undergone BRCA1/2 testing.
methodsAn ovarian cancer risk perception study stratified 16,720 eligible women from the Henry Ford Health System into average-, elevated-, and high-risk groups based on family history. We randomly selected 3,307 subjects and interviewed 2,524 of them (76.3% response rate).
resultsAmong the average-, elevated-, and high-risk groups, 2.3, 10.1, and 20.2%, respectively, reported genetic counseling referrals, and 0.8, 3.3, and 9.5%, respectively, reported having undergone BRCA testing. Personal breast cancer history, high risk, and perceived ovarian cancer risk were associated with both referral and testing. Discussion of family history with a doctor predicted counseling referral, whereas belief that family history influenced risk was the strongest BRCA testing predictor. Women perceiving their cancer risk as much higher than other women their age were twice as likely (95% confidence interval: 2.0-9.6) to report genetic counseling referral.
conclusionIn a health system with ready access to cancer genetic counseling and BRCA testing, women who were at high risk underutilized these services. There were strong associations between perceived ovarian cancer risk and genetic counseling referral, and between a belief that family history influenced risk and BRCA testing.
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