ArticlePloS one2014
Interaction of CPR5 with cell cycle regulators UVI4 and OSD1 in Arabidopsis.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 35 citations in OpenAlex.
- Single-Cell Transcriptomics Reveals FLS2-Dependent Hypoxia Signaling and ERF13-Mediated Transcription During flg22-Triggered Immunity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ubiquitin-Mediated Proteolysis as a Regulator of the Plant Defense-Growth Balance.Plants (Basel, Switzerland) · 2026Review
- StOSD1/UVI4 is crucial for accurate mitotic progression and the maintenance of leaf morphology in potato.BMC plant biology · 2025Article
- Cancer therapy by cyclin-dependent kinase inhibitors (CDKIs): bench to bedside.EXCLI journal · 2024Review
- Ontogenic stage-associated SA response contributes to leaf age-dependent resistance inFrontiers in plant science · 2024Article
- The DcPS1 cooperates with OSDLa during pollen development and 2n gamete production in carnation meiosis.BMC plant biology · 2022Article
- Arabidopsis CPR5 plays a role in regulating nucleocytoplasmic transport of mRNAs in ethylene signaling pathway.Plant cell reports · 2022Article
- Genome-Wide Identification and Characterization ofFrontiers in genetics · 2022Article
- Genome sequencing of turmeric provides evolutionary insights into its medicinal properties.Communications biology · 2021Article
- A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation.The Plant cell · 2018Article
- DNA Synthesis Is Activated in Mosquitoes and Human Monocytes During the Induction of Innate Immune Memory.Frontiers in immunology · 2018Article
- Arabidopsis CPR5 regulates ethylene signaling via molecular association with the ETR1 receptor.Journal of integrative plant biology · 2017Article
- Fruit weight is controlled by Cell Size Regulator encoding a novel protein that is expressed in maturing tomato fruits.PLoS genetics · 2017Article
- CPR5 modulates salicylic acid and the unfolded protein response to manage tradeoffs between plant growth and stress responses.The Plant journal : for cell and molecular biology · 2017Article
- Differential Roles of Two Homologous Cyclin-Dependent Kinase Inhibitor Genes in Regulating Cell Cycle and Innate Immunity in Arabidopsis.Plant physiology · 2016Article
- Hormone activities and the cell cycle machinery in immunity-triggered growth inhibition.Journal of experimental botany · 2015Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The impact of cell cycle on plant immunity was indicated by the enhancement of disease resistance with overexpressing OSD1 and UVI4 genes that are negative regulators of cell cycle controller APC (anaphase promoting complex). CPR5 is another gene that is implicated in cell cycle regulation and plant immunity, but its mode of action is not known. Here we report the analysis of genetic requirement for the function of UVI4 and OSD1 in cell cycle progression control and in particular the involvement of CPR5 in this regulation. We show that the APC activator CCS52A1 partially mediates the function of OSD1 and UVI4 in female gametophyte development. We found that the cpr5 mutation suppresses the endoreduplication defect in the uvi4 single mutant and partially rescued the gametophyte development defect in the osd1 uvi4 double mutant while the uvi4 mutation enhances the cpr5 defects in trichome branching and plant disease resistance. In addition, cyclin B1 genes CYCB1;1, CYCB1;2, and CYCB1;4 are upregulated in cpr5. Therefore, CPR5 has a large role in cell cycle regulation and this role has a complex interaction with that of UVI4 and OSD1. This study further indicates an intrinsic link between plant defense responses and cell cycle progression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.