Evidence map›Paper›PMID 24944576›Full record

ArticleEcancermedicalscience2014

Breast cancer and pregnancy: a comparative analysis of a Chilean cohort.

César Sánchez, Francisco Acevedo, Lidia Medina, Carolina Ibáñez, Dravna Razmilic, M Elena Navarro, Mauricio Camus

Abstract read
In one paragraph

Article in Ecancermedicalscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Treatment of Pregnancy-Associated Breast Cancer.Journal of the advanced practitioner in oncology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

César SánchezHaematology-Oncology Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.
Francisco AcevedoHaematology-Oncology Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.
Lidia MedinaHaematology-Oncology Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.
Carolina IbáñezHaematology-Oncology Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.
Dravna RazmilicRadiology Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.
M Elena NavarroRadiology Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.
Mauricio CamusOncology-Surgery Department, Cancer Programme, School of Medicine, Pontificia Universidad Católica de Chile, Diagonal Paraguay 319, Santiago 8330032, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecent reports show that pregnancy-associated breast cancer (PABC) survival is similar to that of non-pregnant young patients. We evaluate the characteristics and prognosis of PABC patients treated in our cancer centre. PATIENTS AND

methodsWe identified patients with invasive PABC who were treated between 1999 and May 2013 and compared their characteristics with a no PABC cohort of similar age.

resultsThe prevalence of PABC was 1% (n = 17). The median age was 35 years (range: 29- 42 years). The initial tumour was suspected clinically in 93% of the cases. Total mastectomy rates were higher in women with PABC (78.6% versus 40.5%, p = 0.02), and more tumours in the PABC group were triple negative, epidermal growth factor type 2 (HER2)-positive, and at advanced stages; however, these differences were not statistically significant. While estimated overall survival at ten years was higher in the non-PABC group (75.5% versus 80.5%, p = 0.043), disease-specific survival (DSS) rate at ten years was not statistically different between groups (83.9% for PABC and 75.5% for unrelated pregnancy BC, p = 0.37).

conclusionsPABC is a rare event. In our cohort, it tended to be more aggressive. Compared with a similar age cohort, the DSS was not worse.

Indexed as

breast cancerpregnancyprognosis

Identifiers

PMID24944576
PMCPMC4049330

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.