ArticleWorld journal of gastroenterology2014
Diabetes mellitus increases risk for colorectal adenomas in younger patients.
Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04477694 (The Effect of Diabetes Mellitus on Hemodynamics, Procedure Times, Anesthetic Consumption and Complications in Colonoscopy Under Sedoanalgesia), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Diabetes Mellitus on Hemodynamics, Procedure Times, Anesthetic Consumption and Complications in Colonoscopy Under Sedoanalgesia
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Type 2 diabetes mellitus and risk of colorectal adenoma: a meta-analysis of observational studies.BMC cancer · 2016Pooled it
- Exploring the associations between colorectal polyps and type 2 diabetes mellitus in a colonoscopy clinic population.ESMO gastrointestinal oncology · 2024Article
- Age-Specific Differences in the Risk of Colorectal Precursor Lesions Among Patients with Type 2 Diabetes Undergoing Surveillance Colonoscopy.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Self-reported Metabolic Risk Factor Associations with Adenomatous, Sessile Serrated, and Synchronous Adenomatous and Sessile Serrated Polyps.Cancer prevention research (Philadelphia, Pa.) · 2021Observational
- Glucose Intolerance and Cancer Risk: A Community-Based Prospective Cohort Study in Shanghai, China.Frontiers in oncology · 2021Article
- Select group of patients might benefit from early colonoscopic screening for colorectal cancer.Surgical endoscopy · 2020Article
- Early-onset colorectal cancer: initial clues and current views.Nature reviews. Gastroenterology & hepatology · 2020Review
- A Review of the Management of Sporadic Colorectal Adenomas in Young People: Is Surveillance Wasted on the Young?Digestive diseases and sciences · 2019Review
- A Comparative Study Evaluating the Incidence of Colorectal Neoplasia(s) in Candidates for Bariatric Surgery by Screening Colonoscopy, 40-49 Versus 50-65 Years Old: a Preliminary Study.Obesity surgery · 2019Article
- Differential relationship between colorectal cancer and diabetes in a nationally representative sample of adults.Journal of diabetes and its complications · 2018Article
- Diabetes mellitus and hyperglycemia control on the risk of colorectal adenomatous polyps: a retrospective cohort study.BMC family practice · 2018Article
- Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?Journal of diabetes and its complications · 2017Review
- Diabetes-induced mechanophysiological changes in the small intestine and colon.World journal of diabetes · 2017Review
- Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population.Oncotarget · 2016Article
- Association between nonalcoholic fatty liver disease and colorectal adenoma: a systematic review and meta-analysis.International journal of clinical and experimental medicine · 2015Article
- Impact of glycemic control on colonoscopy outcomes: bowel preparation and polyp detection.Annals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine if diabetes mellitus (DM) is associated with increased risk of colorectal adenomas in younger subjects.
methodsThis was a retrospective cohort study of 375 patients undergoing index colonoscopy at a single tertiary care center in the United States. Three cohorts of patients matched for exam date and gender were compared: (1) ages 40-49 years with DM; (2) ages 40-49 years without DM; and (3) ages 50-59 years without DM. Data collected included demographics, co-morbidities, colonoscopy and pathology results. Adenoma detection rates (ADR) were calculated and compared. Conditional logistic regression analysis was performed to determine the association between each cohort and ADR.
resultsOne hundred and twenty-five patients ages 40-49 with DM met study eligibility criteria. Patients in the other two cohorts were randomly selected, matching for date of exam and gender. ADR was 14.4% in those ages 40-49 years without DM, 30.4% in those ages 40-49 years with DM, and 32.0% in those ages 50-59 years without DM. Compared to those ages 40-49 years without DM, ADR was higher in those ages 40-49 years with DM (OR = 3.1; 95%CI: 1.5-6.4; P = 0.002) and those ages 50-59 years without DM (OR = 2.9; 95%CI: 1.5-5.6; P = 0.002). There was no difference between the ADR in those ages 40-49 years with DM and those ages 50-59 years without DM (P = 0.83).
conclusionDM was associated with higher risk of colorectal adenomas in patients ages 40-49 years. These subjects harbored as many adenomas as those at the standard screening age of 50-59 years without DM.
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