ArticleWorld journal of gastroenterology2014
Helicobacter pylori eradication in patients with chronic immune thrombocytopenic purpura.
Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 17 citations in OpenAlex.
- Determinants ofBMJ open · 2026Article
- Plasma Metabolomics Identifies the Dysregulated Metabolic Profile of Primary Immune Thrombocytopenia (ITP) Based on GC-MS.Frontiers in pharmacology · 2022Article
- Management of Helicobacter pylori infection: The Bhubaneswar Consensus Report of the Indian Society of Gastroenterology.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- H. pylori infection and extra-gastroduodenal diseases.Journal of biomedical science · 2018Review
- Role ofGastroenterology research and practice · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the effect of Helicobacter pylori (H. pylori) eradication on platelet counts in patients with chronic immune thrombocytopenic purpura (cITP).
methodsA total of 36 cITP patients were included in the study. The diagnosis of H. pylori was done by rapid urease test and Giemsa staining of the gastric biopsy specimen. All H. pylori positive patients received standard triple therapy for 14 d and were subjected for repeat endoscopy at 6 wk. Patients who continued to be positive for H. pylori on second endoscopy received second line salvage therapy. All the patients were assessed for platelet response at 6 wk, 3(rd) and 6(th) months.
resultsOf the 36 patients, 17 were positive for H. pylori infection and eradication was achieved in 16 patients. The mean baseline platelet count in the eradicated patients was 88615.38 ± 30117.93/mm(3) and platelet count after eradication at 6 wk, 3 mo and 6 mo was 143230.77 ± 52437.51/mm(3) (P = 0.003), 152562.50 ± 52892.3/mm(3) (P = 0.0001), 150187.50 ± 41796.68/mm(3) (P = 0.0001) respectively and in the negative patients, the mean baseline count was 71000.00 ± 33216.46/mm(3) and at 6 wk, 3(rd) and 6(th) month follow up was 137631.58 ± 74364.13/mm(3) (P = 0.001), 125578.95 ± 71472.1/mm(3) (P = 0.005), 77210.53 ± 56892.28/mm(3) (P = 0.684) respectively.
conclusionEradication of H. pylori leads to increase in platelet counts in patients with cITP and can be recommended as a complementary treatment with conventional therapy.
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