ArticleCurrent therapeutic research, clinical and experimental2003
Guidelines for the clinical use of albumin: comparison of use in two Italian hospitals and a third hospital without guidelines.
Article in Current therapeutic research, clinical and experimental, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Improving appropriate use of intravenous albumin: results of a single-centre audit and multifaceted intervention.BMJ open quality · 2024Article
- Evaluation of Albumin 25% Use in Critically Ill Patients at a Tertiary Care Medical Center.Hospital pharmacy · 2020Article
- Establishing a hospital transfusion management system promotes appropriate clinical use of human albumin in Japan: a nationwide retrospective study.BMC health services research · 2019Observational
- Overview of Albumin and Its Purification Methods.Advanced pharmaceutical bulletin · 2016Review
- The evaluation of albumin utilization in a teaching university hospital in iran.Iranian journal of pharmaceutical research : IJPR · 2011Article
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4 authors.
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Abstract
backgroundIn the absence of clinical practice guidelines prior to 1999, the consumption of human albumin in the Liguria region of Italy was very high, despite possible adverse effects, limited supply, and significant cost.
objectiveThe purpose of this study was to assess the impact of comprehensive guidelines on the amount of albumin used in 2 general hospitals and to compare it with that of a third general hospital that did not adopt the guidelines.
methodsWe analyzed the influence of the guidelines on albumin use in 2 general hospitals (hospitals 1 and 2) in the Liguria region by comparing albumin consumption during the year before the distribution of the guidelines (1999) with consumption in the 2 years after their distribution (2000 and 2001). We compared these data with those of a third general hospital that did not adopt the guidelines (hospital 3). The parameters considered were total consumption of albumin, consumption per bed, consumption per hospital stay, mean time to discharge, expenditure per bed, and mortality rate.
resultsIn the years 2000 and 2001, the adoption of guidelines reduced albumin consumption in hospitals 1 and 2. In hospital 1, where the release of albumin was carefully controlled by the transfusion service, albumin use per hospital stay decreased 8.7% in 2000 and 7.6% in 2001 from 1999; in hospital 2, use decreased 73.8% and 77.4%, respectively, from 1999. In hospital 3, rejection of the guidelines was coupled with an increase of 2.9% and 8.4%, respectively, in the amount of albumin used per hospital stay. In the years 2000 and 2001, the savings in the expenditure for albumin was ∼17,000 euro in hospital 1 and ∼200,000 euro in hospital 2.
conclusionThis study confirms that the adoption of guidelines may substantially reduce the inappropriate use of albumin and relative costs.
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