ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2014
Phosphate absorption across multiple epithelia in the Pacific hagfish (Eptatretus stoutii).
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Trace metals in the teleost fish gill: biological roles, uptake regulation, and detoxification mechanisms.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Review
- Mechanistic characterization of waterborne selenite uptake in the water flea,Conservation physiology · 2024Article
- In vitro characterisation of calcium influx across skin and gut epithelia of the Pacific hagfish, Eptatretus stoutii.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020Article
- Dropping the base: recovery from extreme hypercarbia in the COJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018Article
- Post-prandial physiology and intestinal morphology of the Pacific hagfish (Eptatretus stoutii).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018Article
- Drinking and water permeability in the Pacific hagfish, Eptatretus stoutii.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2017Article
- Flexible ammonia handling strategies using both cutaneous and branchial epithelia in the highly ammonia-tolerant Pacific hagfish.American journal of physiology. Regulatory, integrative and comparative physiology · 2017Article
- Characterization of the isoforms of type IIb sodium-dependent phosphate cotransporter (Slc34a2) in yellow catfish, Pelteobagrus fulvidraco, and their vitamin DFish physiology and biochemistry · 2017Article
- Determining the functional role of waterborne amino acid uptake in hagfish nutrition: a constitutive pathway when fasting or a supplementary pathway when feeding?Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inorganic phosphate (Pi) is an essential nutrient for all organisms, but in seawater, Pi is a limiting nutrient. This study investigated the primary mechanisms of Pi uptake in Pacific hagfish (Eptatretus stoutii) using ex vivo physiological and molecular techniques. Hagfish were observed to have the capacity to absorb Pi from the environment into at least three epithelial surfaces: the intestine, skin, and gill. Pi uptake in all tissues was concentration dependent, and saturable Pi transport was observed in the skin and gill at <2.0 mmol/l Pi. Gill and intestinal Pi uptake was sodium dependent, but Pi uptake into the skin increased under low sodium conditions. Gill Pi transport exhibited an apparent affinity constant ~0.23-0.6 mmol/l Pi. A complete sequence of a type II sodium phosphate cotransporter (Slc34a) was obtained from the hagfish gill. Phylogenetic analysis of the hagfish Slc34a transporter indicates that it is earlier diverging than, and/or ancestral to, the other identified vertebrate Slc34a transporters (Slc34a1, Slc34a2, and Slc34a3). With the use of RT-PCR, the hagfish Slc34a transcript was detected in the intestine, skin, gill, and kidney, suggesting that this may be the transporter involved in Pi uptake into multiple epithelia in the hagfish. This is the first measurement of Pi uptake across the gill or skin of any vertebrate animal and first sodium phosphate cotransporter identified in hagfish.
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