ArticleHeart and vessels2015
Impact of advanced age on the severity of normotensive pulmonary embolism.
Article in Heart and vessels, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Prognostic impact of the e-TAPSE ratio in intermediate-high risk pulmonary embolism patients.The international journal of cardiovascular imaging · 2024Trial
- Impact of type 2 diabetes mellitus on in-hospital outcomes in patients with ST-elevation myocardial infarction: A nationwide study in Germany.Metabolism open · 2026Article
- Sarcopenia influences usage of reperfusion treatment in patients with pulmonary embolism aged 75 years and older.International journal of cardiology. Heart & vasculature · 2024Article
- Optimal hemodynamic parameters for risk stratification in acute pulmonary embolism patients.Journal of thrombosis and thrombolysis · 2024Review
- Development and validation of a novel model to predict pulmonary embolism in cardiology suspected patients: A 10-year retrospective analysis.Open medicine (Warsaw, Poland) · 2024Article
- A nomogram for predicting the risk of pulmonary embolism in neurology department suspected PE patients: A 10-year retrospective analysis.Frontiers in neurology · 2023Article
- Developing a nomogram-based scoring model to estimate the risk of pulmonary embolism in respiratory department patients suspected of pulmonary embolisms.Frontiers in medicine · 2023Article
- A retrospective observational study investigating the factors associated with right heart failure in patients with primary acute pulmonary embolism and deep vein thrombosis.Journal of general and family medicine · 2020Article
- Sarcopenia.Wiener medizinische Wochenschrift (1946) · 2019Review
- Prognostic role of a new risk index for the prediction of 30-day cardiovascular mortality in patients with acute pulmonary embolism: the Age-Mean Arterial Pressure Index (AMAPI).Heart and vessels · 2017Article
- Epidemiological and outcome data in Japanese patients with deep vein thrombosis with and without malignancy.Heart and vessels · 2017Observational
- Estimation of right ventricular dysfunction by computed tomography pulmonary angiography: a valuable adjunct for evaluating the severity of acute pulmonary embolism.Journal of thrombosis and thrombolysis · 2017Article
- Indications, applications, and outcomes of inferior vena cava filters for venous thromboembolism in Japanese patients.Heart and vessels · 2016Observational
- Profile of Solid Tumor Patients Complicated With Venous Thromboembolism: A 10-Year Retrospective Cross-Sectional Study Based on 1482 Cases.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisObservational
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of pulmonary embolism (PE) increases progressively with age. Less data about the impact of increasing age on the severity of PE are available. The objectives of this study were to investigate the impact of increasing age on the severity of normotensive PE. Retrospective analysis of clinical, laboratory, radiological and echocardiagraphic data of normotensive patients with PE was performed. According to patients' age at the moment of acute PE event, the total number of 129 normotensive PE patients was subdivided into 4 age groups. In age groups 18-59, 60-69, 70-79 and 80-94 years were, respectively, a number of 30, 31, 33 and 35 patients included. Percentage of women in age groups increased with advanced age (P = 0.021). Systolic pulmonary artery pressure (PAP) (P < 0.0001) and frequency of incomplete or complete right bundle-branch block (RBBB) (P = 0.019), of right ventricular dysfunction (RVD) (P = 0.00031) and of submassive PE stadium with intermediate risk (P = 0.0016) increased significantly with growing age. Multivariable regression model confirmed an association between age and submassive PE [OR (per year) 1.04; 95 % CI, 1.02-1.07, P = 0.0020] as well as female gender and submassive PE (OR 2.45; 95 % CI, 1.10-5.50, P = 0.029) and tachycardia and submassive PE (OR 15.33; 95 % CI, 3.45-68.24, P = 0.00034). Advanced age, female gender and tachycardia are risk factors for a submassive PE with intermediate risk in normotensive PE patients. The percentage of PE patients with submassive PE, right ventricular overload, RVD, RBBB, elevated systolic PAP increases with advanced age.
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