Evidence map›Paper›PMID 24940768›Full record

ReviewCritical reviews in eukaryotic gene expression2014

SWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma.

A Mehrotra, G Mehta, S Aras, A Trivedi, I L de la Serna

Abstract readReview
In one paragraph

Review in Critical reviews in eukaryotic gene expression, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. BRAF Gene and Melanoma: Back to the Future.International journal of molecular sciences · 2021
    Review
  6. Pooled Sequencing Analysis of Geese (Frontiers in genetics · 2021
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. BPTF Is Essential for T Cell Homeostasis and Function.Journal of immunology (Baltimore, Md. : 1950) · 2016
    Article
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

A MehrotraDepartment of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, OH.
G MehtaDepartment of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, OH.
S ArasDepartment of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, OH.
A TrivediDepartment of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, OH.
I L de la SernaDepartment of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, Toledo, OH.
University of Toledo · US

Funding

Regulation of Melanocyte Differentiation by SWI/SNF Chromatin Remodeling EnzymesR01AR059379 · NIAMS · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI DE LA SERNA, IVANA L · 2010 to 2014
$1.6M
NIAMS NIH HHS R01 AR059379
6 · The paper itself

Abstract

Epidermal melanocytes are pigment-producing cells derived from the neural crest that protects skin from the damaging effects of solar radiation. Malignant melanoma, a highly aggressive cancer, arises from melanocytes. SWI/SNF enzymes are multiprotein complexes that remodel chromatin structure and have extensive roles in cellular differentiation. Components of the complex have been found to be mutated or lost in several human cancers. This review focuses on studies that implicate SWI/SNF enzymes in melanocyte differentiation and in melanoma.

Indexed as

Cell DifferentiationChromatin Assembly and DisassemblyChromosomal Proteins, Non-HistoneHumansMelanocytesMelanomaTranscription FactorsChromosomal Proteins, Non-HistoneSWI-SNF-B chromatin-remodeling complexTranscription Factors

Identifiers

PMID24940768
PMCPMC4104388
OpenAlexW2068538563

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.