Evidence map›Paper›PMID 24940430›Full record

ArticleExperimental and therapeutic medicine2014

Effects of progesterone on hippocampal ultrastructure and expression of inflammatory mediators in neonatal rats with hypoxic-ischemic brain injury.

Xiaojuan Li, Junhe Zhang, Xiaoqian Zhu, Ruanling Hou, Xinjuan Li, Xianhong Dong, Xiaoyin Wang, Chengbiao Lu

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiaojuan LiDepartment of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Junhe ZhangDepartment of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Xiaoqian ZhuDepartment of Ophthalmology of the Third Affiliated Hospital, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Ruanling HouDepartment of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Xinjuan LiDepartment of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Xianhong DongDepartment of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Xiaoyin WangDepartment of Biochemistry and Molecular Biology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Chengbiao LuDepartment of Physiology and Neurobiology, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
Xinxiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progesterone (PROG) has been shown to exhibit a protective function against hypoxic-ischemic brain damage. The aim of the present study was to study the effects of PROG in a neonatal rat model of hypoxic-ischemic brain injury. A total of 30 Wistar rats, aged 7 days, were randomly divided into three groups: Sham, model and PROG. The rats in the model and PROG groups underwent a left common carotid artery ligation and were placed in a sealed container at 37°C with 8% O

Indexed as

brain damagehypoxia-ischemianuclear factor-κBprogesteronetumor necrosis factor-αultrastructure

Identifiers

PMID24940430
PMCPMC3991529
OpenAlexW2105129033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.