Evidence map›Paper›PMID 24940427›Full record

ArticleExperimental and therapeutic medicine2014

Enforced expression of microRNA-21 influences the replication of varicella-zoster virus by triggering signal transducer and activator of transcription 3.

Yan Li, Rina Wu, Zhongrong Liu, Jianyong Fan, Huilan Yang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yan LiSouthern Medical University, Guangzhou, Guangdong 510515, P.R. China ; Department of Dermatology, Affiliated Hospital of Inner Mongolia Medical University, Hohehot, Inner Mongolia 010050, P.R. China.
Rina WuDepartment of Dermatology, Affiliated Hospital of Inner Mongolia Medical University, Hohehot, Inner Mongolia 010050, P.R. China.
Zhongrong LiuDepartment of Dermatology, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong 510010, P.R. China.
Jianyong FanDepartment of Dermatology, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong 510010, P.R. China.
Huilan YangDepartment of Dermatology, General Hospital of Guangzhou Military Command of PLA, Guangzhou, Guangdong 510010, P.R. China.
General Hospital of Guangzhou Military Command · CNInner Mongolia Medical University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella-zoster virus (VZV) causes chronic pain and serious complications, including zoster paresis. However, the mechanism of VZV replication, a critical part of VZV pathogenesis, remains largely unknown and was investigated in the present study. The upregulation of microRNA-21 (miR-21) was identified following VZV infection

Indexed as

microRNA-21signal transducer and activator of transcription 3varicella-zoster virus

Identifiers

PMID24940427
PMCPMC3991484
OpenAlexW2057187122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.