ArticleNanoscale research letters2014
Tunable biphasic drug release from ethyl cellulose nanofibers fabricated using a modified coaxial electrospinning process.
Article in Nanoscale research letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Electrospun Nanofibers: Shaping the Future of Controlled and Responsive Drug Delivery.Materials (Basel, Switzerland) · 2023Review
- Article
- Cellulose-Based Nanofibers Processing Techniques and Methods Based on Bottom-Up Approach-A Review.Polymers · 2022Review
- Review
- Electrosprayed Ethyl Cellulose Core-Shell Microcapsules for the Encapsulation of Probiotics.Pharmaceutics · 2021Article
- Electrospun wound dressings containing bioactive natural products: physico-chemical characterization and biological assessment.Biomaterials research · 2021Article
- Effects of Polyvinylpyrrolidone and Ethyl Cellulose in Polyurethane Electrospun Nanofibers on Morphology and Drug Release Characteristics.Turkish journal of pharmaceutical sciences · 2020Article
- Antioxidant and Antitumor Activities of Novel Quercetin-Loaded Electrospun Cellulose Acetate/Polyethylene Glycol Fibrous Materials.Antioxidants (Basel, Switzerland) · 2020Article
- 3D printing of a wearable personalized oral delivery device: A first-in-human study.Science advances · 2018Article
- Influence of Working Temperature on The Formation of Electrospun Polymer Nanofibers.Nanoscale research letters · 2017Article
- Coaxial Electrospinning and Characterization of Core-Shell Structured Cellulose Nanocrystal Reinforced PMMA/PAN Composite Fibers.Materials (Basel, Switzerland) · 2017Article
- Increased cellular uptake of lauryl gallate loaded in superparamagnetic poly(methyl methacrylate) nanoparticles due to surface modification with folic acid.Journal of materials science. Materials in medicine · 2016Article
- Epidural administration of neostigmine-loaded nanofibers provides extended analgesia in rats.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2014Article
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Authors and funding
4 authors.
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Abstract
This manuscript reports a new type of drug-loaded core-shell nanofibers that provide tunable biphasic release of quercetin. The nanofibers were fabricated using a modified coaxial electrospinning process, in which a polyvinyl chloride (PVC)-coated concentric spinneret was employed. Poly (vinyl pyrrolidone) (PVP) and ethyl cellulose (EC) were used as the polymer matrices to form the shell and core parts of the nanofibers, respectively. Scanning and transmission electron microscopy demonstrated that the nanofibers had linear morphologies and core-shell structures. The quercetin was found to be present in the nanofibers in the amorphous physical status, on the basis of X-ray diffraction results. In vitro release profiles showed that the PVP shell very rapidly freed its drug cargo into the solution, while the EC core provided the succedent sustained release. Variation of the drug loading permitted the release profiles to be tuned.
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