Evidence map›Paper›PMID 24940137›Full record

ArticleOchsner journal2014

Two Cases of Fulminant Hepatic Failure from Amanita phalloides Poisoning Treated Additively by Homeopathy.

Michael Frass, Petko Zagorchev, Vasilka Yurukova, Beatrix Wulkersdorfer, Karin Thieves, Konstantin Zedtwitz-Liebenstein, Willfried Bursch, Alan David Kaye

Open access · greenAbstract readCase Reports
In one paragraph

Article in Ochsner journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Letters to the editor.Ochsner journal · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michael FrassDepartment of Medicine I, Intensive Care Unit, Medical University of Vienna, Austria.
Petko ZagorchevAnesthesiology and Toxicology, Department of Anesthesiology and Critical Care, Hospital for Active Therapy, Shumen, Bulgaria.
Vasilka YurukovaInternal Medicine, Clinic for Homeopathy, Plovdiv, Bulgaria.
Beatrix WulkersdorferDepartment of Medicine I, Intensive Care Unit, Medical University of Vienna, Austria.
Karin ThievesSola Salus, Institute for Homeopathic Research, Geilenkirchen, Germany.
Konstantin Zedtwitz-LiebensteinDepartment of Medicine I, Intensive Care Unit, Medical University of Vienna, Austria.
Willfried BurschDepartment of Internal Medicine I, Institute of Cancer Research, Medical University of Vienna, Austria.
Alan David KayeDepartments of Anesthesiology and Pharmacology, Louisiana State University Health Sciences Center, New Orleans, LA.
Medical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntoxication with Amanita phalloides is associated with high morbidity and mortality. Treatment therapies include general support, toxin elimination, pharmacotherapy with agents such as the hepatoprotective agent silibinin, and, in extreme states, liver transplantation. Despite these therapeutic interventions, mortality remains relatively high. CASE REPORTS: We present reports of 2 patients with severe hepatic failure following intoxication with Amanita phalloides. Both patients were admitted to the intensive care unit; 1 patient suffered from hepatic failure solely, and the second patient experienced severe 5-organ failure. In addition to conventional intensive care treatment, both patients were treated additively with classical homeopathy. The 2 patients survived without any residual pathological sequelae.

conclusionBased on the 2 cases, including 1 extreme situation, we suggest that adjunctive homeopathic treatment has a role in the treatment of acute Amanita phalloides-induced toxicity following mushroom poisoning. Additional studies may clarify a more precise dosing regimen, standardization, and better acceptance of homeopathic medicine in the intensive care setting.

Indexed as

Amanitinshomeopathytoxins–biologicaltoxophallin–Amanita phalloides

Identifiers

PMID24940137
PMCPMC4052594
OpenAlexW2103099833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.