ReviewInternational journal of chronic obstructive pulmonary disease2014
Activity restriction in mild COPD: a challenging clinical problem.
Review in International journal of chronic obstructive pulmonary disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02566915 (Effects of Expiratory Positive Airway Pressure on Dyspnea and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Expiratory Positive Airway Pressure on Dyspnea and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Systematic review of the association between exercise tests and patient-reported outcomes in patients with chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2017Pooled it
- A pilot crossover trial assessing the exercise performance patients chronic obstructive pulmonary disease.Scientific reports · 2022Trial
- Effects of high-flow nasal cannula with oxygen on self-paced exercise performance in COPD: A randomized cross-over trial.Medicine · 2021Trial
- Clinical characteristics and longitudinal prognosis of patients with mild-to-moderate chronic obstructive pulmonary disease progressing from different lung function trajectories.Journal of thoracic disease · 2026Article
- CAPTURE and PUMA as Case-Finding Tools in Patients at Risk of COPD-A Multicenter Mexican Experience.Journal of clinical medicine · 2025Article
- Feasibility and acute physiological responses to supramaximal high-intensity interval training in COPD: a randomised crossover trial.ERJ open research · 2025Article
- Change is in the air: key questions on the 'Treatable Traits' model for chronic airway diseases in primary care.NPJ primary care respiratory medicine · 2024Review
- Perspectives of Patients With Chronic Respiratory Diseases and Medical Professionals on Pulmonary Rehabilitation in Pune, India: Qualitative Analysis.JMIR formative research · 2023Article
- To Act or Not to Act-a Sense of Control Is Important for People With Chronic Obstructive Pulmonary Disease to Increase Physical Activity: Grounded Theory Study.JMIR formative research · 2023Article
- PUMA screening tool to detect COPD in high-risk patients in Chinese primary care-A validation study.PloS one · 2022Article
- Pulmonary function testing in COPD: looking beyond the curtain of FEV1.NPJ primary care respiratory medicine · 2021Review
- Walking distance in incremental shuttle walking test as a predictor of physical activity in patients diagnosed with low-risk chronic obstructive pulmonary disease.SAGE open medicine · 2021Article
- Implications of Managing Chronic Obstructive Pulmonary Disease in Cardiovascular Diseases.Tuberculosis and respiratory diseases · 2021Article
- Physical Activity and Sedentary Behaviour Patterns in 326 Persons with COPD before Starting a Pulmonary Rehabilitation: A Cluster Analysis.Journal of clinical medicine · 2019Article
- Weighing the evidence for pharmacological treatment interventions in mild COPD; a narrative perspective.Respiratory research · 2019Review
- Importance of the relationship between symptoms and self-reported physical activity level in stable COPD based on the results from the SPACE study.Respiratory research · 2019Observational
- Activity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions.International journal of chronic obstructive pulmonary disease · 2019Review
- Effects of pulmonary rehabilitation in patients with mild-to-moderate chronic obstructive pulmonary disease: Bottom of an iceberg.Turkish journal of physical medicine and rehabilitation · 2018Article
- The use of COPD maintenance therapy following spirometry in General Practice.European clinical respiratory journal · 2016Article
- Hand grip strength is associated with forced expiratory volume in 1 second among subjects with COPD: report from a population-based cohort study.International journal of chronic obstructive pulmonary disease · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dyspnea, exercise intolerance, and activity restriction are already apparent in mild chronic obstructive pulmonary disease (COPD). However, patients may not seek medical help until their symptoms become troublesome and persistent and significant respiratory impairment is already present; as a consequence, further sustained physical inactivity may contribute to disease progression. Ventilatory and gas exchange impairment, cardiac dysfunction, and skeletal muscle dysfunction are present to a variable degree in patients with mild COPD, and collectively may contribute to exercise intolerance. As such, there is increasing interest in evaluating exercise tolerance and physical activity in symptomatic patients with COPD who have mild airway obstruction, as defined by spirometry. Simple questionnaires, eg, the modified British Medical Research Council dyspnea scale and the COPD Assessment Test, or exercise tests, eg, the 6-minute or incremental and endurance exercise tests can be used to assess exercise performance and functional status. Pedometers and accelerometers are used to evaluate physical activity, and endurance tests (cycle or treadmill) using constant work rate protocols are used to assess the effects of interventions such as pulmonary rehabilitation. In addition, alternative outcome measurements, such as tests of small airway dysfunction and laboratory-based exercise tests, are used to measure the extent of physiological impairment in individuals with persistent dyspnea. This review describes the mechanisms of exercise limitation in patients with mild COPD and the interventions that can potentially improve exercise tolerance. Also discussed are the benefits of pulmonary rehabilitation and the potential role of pharmacologic treatment in symptomatic patients with mild COPD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.