ReviewMolecular neurobiology2015
The effects of stress on glutamatergic transmission in the brain.
Review in Molecular neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Exploring metabolomic dynamics in acute stress disorder: amino acids, lipids, and carbohydrates.Frontiers in genetics · 2024Review
- Infection with an acanthocephalan helminth reduces anxiety-like behaviour in crustacean host.Scientific reports · 2022Article
- An overview of the molecular and physiological antidepressant mechanisms of physical exercise in animal models of depression.Molecular biology reports · 2022Review
- DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study.Scientific reports · 2021Article
- A Role for mir-26a in Stress: A Potential sEV Biomarker and Modulator of Excitatory Neurotransmission.Cells · 2020Article
- Impact of autism-associated genetic variants in interaction with environmental factors on ADHD comorbidities: an exploratory pilot study.Journal of neural transmission (Vienna, Austria : 1996) · 2019Article
- Prefrontal glutamate levels predict altered amygdala-prefrontal connectivity in traumatized youths.Psychological medicine · 2019Article
- Recovery of Chronic Stress-Triggered Changes of Hippocampal Glutamatergic Transmission.Neural plasticity · 2018Article
- Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression.Drugs · 2017Review
- Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence.Neural plasticity · 2017Article
- Article
- Transgenerational Inheritance of Paternal Neurobehavioral Phenotypes: Stress, Addiction, Ageing and Metabolism.Molecular neurobiology · 2016Review
- Relationship of recent stress to amygdala volume in depressed and healthy adults.Journal of affective disorders · 2016Article
- Mental abilities and performance efficacy under a simulated 480-m helium-oxygen saturation diving.Frontiers in psychology · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stress leads to detrimental effects on brain functions and results in various diseases. Recent studies highlight the involvement of glutamatergic transmission in pathogenesis of depressive behaviors and fears. Acute stress generates different impacts on the excitatory transmission compared to chronic stress. Different neuromodulators and epigenetic factors also participate in the alteration of synaptic transmission and the regulation of synaptic plasticity. Restoration of the glutamatergic transmission in stress-affected brain areas therefore provides novel directions of therapeutic interventions against stress.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.