Evidence map›Paper›PMID 24938712›Full record

ArticleJournal of the American Heart Association2014

Clinical prediction model suitable for assessing hospital quality for patients undergoing carotid endarterectomy.

Neil J Wimmer, John A Spertus, Kevin F Kennedy, H Vernon Anderson, Jeptha P Curtis, William S Weintraub, Mandeep Singh, John S Rumsfeld, Frederick A Masoudi, Robert W Yeh

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Neil J WimmerBrigham and Women's Hospital and Harvard Medical School, Boston, MA (N.J.W.).
John A SpertusSaint Luke's Mid-America Heart Institute, Kansas City, MO (J.A.S., K.F.K.).
Kevin F KennedySaint Luke's Mid-America Heart Institute, Kansas City, MO (J.A.S., K.F.K.).
H Vernon AndersonUniversity of Texas Health Science Center, Houston, TX (V.A.).
Jeptha P CurtisYale University School of Medicine, New Haven, CT (J.P.C.).
William S WeintraubChristiana Health Care, Newark, DE (W.S.W.).
Mandeep SinghMayo Clinic, Rochester, MN (M.S.).
John S RumsfeldDenver Veterans Affairs Medical Center, Denver, CO (J.S.R.).
Frederick A MasoudiUniversity of Colorado, Aurora, CO (F.A.M.).
Robert W YehMassachusetts General Hospital and Harvard Medical School, Boston, MA (R.W.Y.).

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
NCATS NIH HHS UL1 TR000135
6 · The paper itself

Abstract

backgroundAssessing hospital quality in the performance of carotid endarterectomy (CEA) requires appropriate risk adjustment across hospitals with varying case mixes. The aim of this study was to develop and validate a prediction model to assess the risk of in-hospital stroke or death after CEA that could aid in the assessment of hospital quality. METHODS AND

resultsPatients from National Cardiovascular Data Registry (NCDR)'s Carotid Artery Revascularization and Endarterectomy (CARE) Registry undergoing CEA without acute evolving stroke from 2005 to 2013 were included. In-hospital stroke or death was modeled using hierarchical logistic regression with 20 candidate variables and accounting for hospital-level clustering. Internal validation was achieved with bootstrapping; model discrimination and calibration were assessed. A total of 213 (1.7%) primary end point events occurred during 12 889 procedures. Independent predictors of stroke or death included age, prior peripheral artery disease, diabetes mellitus, prior coronary artery disease, having a symptomatic carotid lesion, having a contralateral carotid occlusion, or having New York Heart Association Class III or IV heart failure. The model was well calibrated and demonstrated moderate discriminative ability (c-statistic 0.65). The NCDR CEA score was then developed to support simple, prospective risk quantification in the clinical setting.

conclusionsThe NCDR CEA score, comprising 7 clinical variables, predicts in-hospital stroke or death after CEA. This model can be used to estimate hospital risk-adjusted outcomes for CEA and to assist with the assessment of hospital quality.

Indexed as

AgedAged, 80 and overAge FactorsEndarterectomy, CarotidFemaleHospitalsHumansLogistic ModelsMaleModels, StatisticalQuality Assurance, Health CareRegistriesStrokeUnited Statescarotid endarterectomyrisk predictionstroke

Identifiers

PMID24938712
PMCPMC4309056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.