ArticleJAMA2014
Exercise for depression.
Article in JAMA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03731728 (The Effectiveness of Group CBT and Exercise in Management of Depression), which is not on this map. Cited by 59 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Group CBT and Exercise in Management of Depression: A Three Arm Randomized Controlled Pilot Trial
Who cites it
59 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- A Handful of Details to Ensure the Experimental Reproducibility on the FORCED Running Wheel in Rodents: A Systematic Review.Frontiers in endocrinology · 2021Pooled it
- Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults: A 2-Sample Mendelian Randomization Study.JAMA psychiatry · 2019Pooled it
- Quantifying the placebo effect in psychological outcomes of exercise training: a meta-analysis of randomized trials.Sports medicine (Auckland, N.Z.) · 2015Pooled it
- The Effects of Exercise on Cognitive Recovery after Acquired Brain Injury in Animal Models: A Systematic Review.Neural plasticity · 2015Pooled it
- Urge Coping Mediates the Relationship Between Physical Activity and Smoking Outcomes in a Sample of Premenopausal Women Intending to Quit Smoking.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- Step away from depression-results from a multicenter randomized clinical trial with a pedometer intervention during and after inpatient treatment of depression.European archives of psychiatry and clinical neuroscience · 2024Trial
- Effects of Cortisol Administration on Resting-State Functional Connectivity in Women with Depression.Psychiatry research. Neuroimaging · 2024Trial
- Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder.Obesity (Silver Spring, Md.) · 2021Trial
- Effects of a group-based lifestyle medicine for depression: A pilot randomized controlled trial.PloS one · 2021Trial
- Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI.NeuroImage. Clinical · 2020Trial
- Effects of a randomized exercise trial on physical activity, psychological distress and quality of life in older adults.General hospital psychiatry · 2017Trial
- Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial.European archives of psychiatry and clinical neuroscience · 2016Trial
- Atypical depressive symptoms as a predictor of treatment response to exercise in Major Depressive Disorder.Journal of affective disorders · 2016Trial
- Cardiac Risk Markers and Response to Depression Treatment in Patients With Coronary Heart Disease.Psychosomatic medicine · 2016Trial
- Trial
- Correlation of physical activity with positive and negative affect and frontal lateralization in college students with depressive symptoms.Scientific reports · 2026Article
- Effect of regular physical activities and daytime nap intervention on enhancing mental health and self-esteem in healthy participants.Journal of education and health promotion · 2025Article
- Unpacking differences in post-exercise affective experiences between physically underactive and active individuals.Journal of behavioral medicine · 2024Article
- The impact of exercise intensity on depression in fibromyalgia: a randomized controlled trial.Frontiers in psychology · 2024Article
- Effect of acute and long-term exercise on leptin levels in depressed outpatients.BMC public health · 2023Article
Corrections and comments
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- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
clinical questionIs exercise an effective treatment for depression? BOTTOM LINE: Exercise is associated with a greater reduction in depression symptoms compared with no treatment, placebo, or active control interventions, such as relaxation or meditation. However, analysis of high-quality studies alone suggests only small benefits.
Indexed as
Identifiers
24938566What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.