Evidence map›Paper›PMID 24938508›Full record

ArticleJournal of exposure science & environmental epidemiology2015

Ambient polycyclic aromatic hydrocarbons and pulmonary function in children.

Amy M Padula, John R Balmes, Ellen A Eisen, Jennifer Mann, Elizabeth M Noth, Frederick W Lurmann, Boriana Pratt, Ira B Tager, Kari Nadeau, S Katharine Hammond

Open access · bronzeAbstract read
In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 62 citations in OpenAlex.

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  19. Environmental and individual PAH exposures near rural natural gas extraction.Environmental pollution (Barking, Essex : 1987) · 2018
    Article
  20. 2-Naphthol Levels and Allergic Disorders in Children.International journal of environmental research and public health · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Amy M PadulaDepartment of Pediatrics - Neonatology, School of Medicine, Stanford University, Stanford, CA, USA.
John R Balmes1] Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA [2] Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Ellen A EisenDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Jennifer MannDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Elizabeth M NothDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Frederick W LurmannSonoma Technology, Petaluma, CA, USA.
Boriana PrattDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Ira B TagerDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
Kari NadeauDepartment of Pediatrics - Neonatology, School of Medicine, Stanford University, Stanford, CA, USA.
S Katharine HammondDivision of Environmental Health Sciences, School of Public Health, University of California, Berkeley, Berkeley, CA, USA.
University of California, Berkeley · USBerkeley Public Health Division · USStanford University · USSonoma Technology (United States) · US

Funding

SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierU01AI147462 · NIAID · STANFORD UNIVERSITY · PI Mary Johnson, GIDEON LACK · 2020 to 2026
$14.0M
UC Berkeley/Stanford Children's Enviromental Health CenterP01ES022849 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R · 2013 to 2018
$4.2M
Fresno Asthmatic Children's Environment Study (FACES)R01HL081521 · NHLBI · UNIVERSITY OF CALIFORNIA BERKELEY · PI TAGER, IRA B · 2006 to 2010
$3.8M
Phenotyping/Epigenetic studies of PAH-associated Treg impairment in asthmaR01ES020926 · NIEHS · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2012 to 2016
$2.5M
Berkeley Center for Environmental Public Health TrackingU19EH000097 · EH · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R · 2005 to 2009
$1.8M
Project 3: Ambient Pollutants/Bioaerosol Effects on Treg FunctionP20ES018173 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HAMMOND, S KATHARINE · 2010 to 2012
$895k
Traffic-related air pollution, social factors and adverse birth outcomesK99ES021470 · NIEHS · STANFORD UNIVERSITY · PI PADULA, AMY MICHELLE · 2013 to 2014
$254k
NCEH CDC HHS 5U19EH000097-04NCEH CDC HHS U19 EH000097NHLBI NIH HHS R01 HL081521NIAID NIH HHS U01 AI147462NIEHS NIH HHS K99 ES021470NIEHS NIH HHS K99ES021470NIEHS NIH HHS L40 ES023163NIEHS NIH HHS P01 ES022849NIEHS NIH HHS P01ES022849NIEHS NIH HHS P20 ES018173NIEHS NIH HHS R01 ES020926NIEHS NIH HHS R01ES020926
6 · The paper itself

Abstract

Few studies have examined the relationship between ambient polycyclic aromatic hydrocarbons (PAHs) and pulmonary function in children. Major sources include vehicular emissions, home heating, wildland fires, agricultural burning, and power plants. PAHs are an important component of fine particulate matter that has been linked to respiratory health. This cross-sectional study examines the relationship between estimated individual exposures to the sum of PAHs with 4, 5, or 6 rings (PAH456) and pulmonary function tests (forced expiratory volume in one second (FEV1) and forced expiratory flow between 25% and 75% of vital capacity) in asthmatic and non-asthmatic children. We applied land-use regression to estimate individual exposures to ambient PAHs for averaging periods ranging from 1 week to 1 year. We used linear regression to estimate the relationship between exposure to PAH456 with pre- and postbronchodilator pulmonary function tests in children in Fresno, California (N=297). Among non-asthmatics, there was a statistically significant association between PAH456 during the previous 3 months, 6 months, and 1 year and postbronchodilator FEV1. The magnitude of the association increased with the length of the averaging period ranging from 60 to 110 ml decrease in FEV1 for each 1 ng/m(3) increase in PAH456. There were no associations with PAH456 observed among asthmatic children. We identified an association between annual PAHs and chronic pulmonary function in children without asthma. Additional studies are needed to further explore the association between exposure to PAHs and pulmonary function, especially with regard to differential effects between asthmatic and non-asthmatic children.

Indexed as

AdolescentAir PollutantsAir PollutionAsthmaCaliforniaChildCross-Sectional StudiesEnvironmental MonitoringFemaleForced Expiratory Flow RatesForced Expiratory VolumeHumansInhalation ExposureLinear ModelsLungMaleAir PollutantsPolycyclic Aromatic Hydrocarbons

Identifiers

PMID24938508
PMCPMC4270934
OpenAlexW1973204751

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.