Evidence map›Paper›PMID 24938369›Full record

Trial reportAddiction (Abingdon, England)2014

Smoking cessation in smokers who smoke menthol and non-menthol cigarettes.

Stevens S Smith, Michael C Fiore, Timothy B Baker

Abstract readComparative StudyHistorical ArticleRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Correlates and prevalence of menthol cigarette use among adults with serious mental illness.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2015
    Trial
  11. Article
  12. Article
  13. Use of Flavored and Modified Risk Smokeless Tobacco Products Among American Indian Adults.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  14. A Method for Amending Loose Smokeless Tobacco With Menthol for Administration in Clinical Studies.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Menthol and Other Flavor Chemicals in Cigarettes from Vietnam and the Philippines.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stevens S SmithDepartment of Medicine, University of Wisconsin School of Medicine and Public Health (UWSMPH), Madison, WI, USA; Center for Tobacco Research and Intervention, UWSMPH, Madison, WI, USA.
Michael C Fiore
Timothy B Baker

Funding

Testing Relapse Recovery Intervention ComponentsP01CA180945 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B, FIORE, MICHAEL C · 2014 to 2023
$23.0M
Enhancing the Effectiveness of Varenicline Based Smoking Cessation TreatmentR01HL109031 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B, STEIN, JAMES H · 2011 to 2020
$17.5M
Transforming The Treatment of Tobacco Use in Health Care: Seizing The Potential of the Electronic Health Record to Deliver Comprehensive Chronic Care Treatment for SmokingR35CA197573 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI MICHAEL C FIORE · 2015 to 2026
$10.7M
Tobacco Dependence: Treatment and OutcomesP50DA019706 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI FIORE, MICHAEL C · 2004 to 2008
$8.6M
Training in Translational Tobacco ScienceK05CA139871 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TIMOTHY B · 2008 to 2012
$850k
NCI NIH HHS K05 CA139871NCI NIH HHS K05CA139871NCI NIH HHS P01 CA180945NHLBI NIH HHS 3R01HL109031-02S1NHLBI NIH HHS R01 HL109031NIDA NIH HHS P50 DA019706
6 · The paper itself

Abstract

aimsTo assess the relations of menthol cigarette use with measures of cessation success in a large comparative effectiveness trial (CET).

designParticipants were randomized to one of six medication treatment conditions in a randomized double-blind, placebo-controlled clinical trial. All participants received six individual counseling sessions.

settingCommunity-based smokers in two communities in Wisconsin, USA.

participantsA total of 1504 adult smokers who smoked at least 10 cigarettes per day during the past 6 months and reported being motivated to quit smoking. The analysis sample comprised 1439 participants: 814 white non-menthol smokers, 439 white menthol smokers and 186 African American (AA) menthol smokers. There were too few AA non-menthol smokers (n = 16) to be included in the analyses.

interventionsNicotine lozenge, nicotine patch, bupropion sustained release, nicotine patch + nicotine lozenge, bupropion + nicotine lozenge and placebo. MEASUREMENTS: Biochemically confirmed 7-day point-prevalence abstinence assessed at 4, 8 and 26 weeks post-quit.

findingsIn longitudinal abstinence analyses (generalized estimating equations) controlling for cessation treatment, menthol smoking was associated with reduced likelihood of smoking cessation success relative to non-menthol smoking [model-based estimates of abstinence = 31 versus 38%, respectively; odds ratio (OR) = 0.71, 95% confidence interval (CI) = 0.59, 0.86]. In addition, among menthol smokers, AA women were at especially high risk of cessation failure relative to white women (estimated abstinence = 17 versus 35%, respectively; OR = 2.63, 95% CI = 1.75, 3.96; estimated abstinence rates for AA males and white males were both 30%, OR = 1.06, 95% CI = 0.60, 1.66).

conclusionIn the United States, smoking menthol cigarettes appears to be associated with reduced cessation success compared with non-menthol smoking, especially in African American females.

Indexed as

MentholTobacco ProductsAdministration, CutaneousAdultBupropionCombined Modality TherapyCounselingDouble-Blind MethodDrug Therapy, CombinationHistory, 15th CenturyHumansLongitudinal StudiesMaleNicotineSex FactorsSmoking CessationBupropionMentholNicotineClinical trialgendergeneralized estimating equationslongitudinalmentholrace/ethnicitysmoking cessationtobacco

Identifiers

PMID24938369
PMCPMC4443703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.