Evidence map›Paper›PMID 24937017›Full record

Trial reportContemporary clinical trials2014

Strategies and Opportunities to STOP Colon Cancer in Priority Populations: design of a cluster-randomized pragmatic trial.

Gloria D Coronado, William M Vollmer, Amanda Petrik, Stephen H Taplin, Timothy E Burdick, Richard T Meenan, Beverly B Green

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01742065 (Strategies and Opportunities to Stop Colon Cancer in Priority Populations), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01742065 nacompletednot on this map

Strategies and Opportunities to Stop Colon Cancer in Priority Populations

TypeinterventionalSponsorKaiser PermanenteRan2013 to 2018Enrolled62,155ConditionsColorectal CancerArmsAuto Plus
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Effectiveness and Cost of an Enhanced Mailed Fecal Test Outreach Colorectal Cancer Screening Program: Findings from the PROMPT Stepped-Wedge Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Article
  15. The Reach of Calls and Text Messages for Mailed FIT Outreach in the PROMPT Stepped-Wedge Colorectal Cancer Screening Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  16. Article
  17. Review
  18. Pragmatic clinical trial design in emergency medicine: Study considerations and design types.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gloria D CoronadoThe Center for Health Research, Kaiser Permanente Northwest, 3800 N. Interstate Avenue, Portland, OR 97227, USA. Electronic address: Gloria.d.coronado@kpchr.org.
William M VollmerThe Center for Health Research, Kaiser Permanente Northwest, 3800 N. Interstate Avenue, Portland, OR 97227, USA. Electronic address: William.vollmer@kpchr.org.
Amanda PetrikThe Center for Health Research, Kaiser Permanente Northwest, 3800 N. Interstate Avenue, Portland, OR 97227, USA. Electronic address: Amanda.f.petrik@kpchr.org.
Stephen H TaplinNational Cancer Institute, Process of Care Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, 9609 Medical Center Drive, Bethesda, MD 20892-9760, USA. Electronic address: Taplins@mail.nih.gov.
Timothy E BurdickOCHIN, Inc., 1881 SW Naito Parkway, Portland, OR 97201, USA; Department of Family Medicine Oregon Health & Sciences University, 4411 SW Vermont Street, Portland, OR 97219, USA. Electronic address: burdickt@ochin.org.
Richard T MeenanThe Center for Health Research, Kaiser Permanente Northwest, 3800 N. Interstate Avenue, Portland, OR 97227, USA. Electronic address: Richard.meenan@kpchr.org.
Beverly B GreenGroup Health Research Institute, 1730 Minor Avenue, Suite 1600, Seattle, WA 98101, USA. Electronic address: Green.b@ghc.org.

Funding

Strategies and Opportunities to Stop Colon Cancer in Priority PopulationsUH3CA188640 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORONADO, GLORIA D · 2014 to 2017
$6.1M
Strategies and Opportunities to Stop Colon Cancer in Priority PopulationsUH2AT007782 · NCCIH · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORONADO, GLORIA D, DEVOE, JENNIFER E · 2012 to 2013
$859k
NCCIH NIH HHS UH2 AT007782NCCIH NIH HHS UH2AT007782NCI NIH HHS 4UH3CA188640-02NCI NIH HHS UH3 CA188640
6 · The paper itself

Abstract

backgroundColorectal cancer is the second-leading cause of cancer deaths in the United States. The Strategies and Opportunities to Stop Colorectal Cancer (STOP CRC) in Priority Populations study is a pragmatic trial and a collaboration between two research institutions and a network of more than 200 safety net clinics. The study will assess the effectiveness of a system-based intervention designed to improve the rates of colorectal-cancer screening using fecal immunochemical testing (FIT) in federally qualified health centers in Oregon and Northern California. MATERIAL AND

methodsSTOP CRC is a cluster-randomized comparative-effectiveness pragmatic trial enrolling 26 clinics. Clinics will be randomized to one of two arms. Clinics in the intervention arm (1) will use an automated, data-driven, electronic health record-embedded program to identify patients due for colorectal screening and mail FIT kits (with pictographic instructions) to them; (2) will conduct an improvement process (e.g. Plan-Do-Study-Act) to enhance the adoption, reach, and effectiveness of the program. Clinics in the control arm will provide opportunistic colorectal-cancer screening to patients at clinic visits. The primary outcomes are: proportion of age- and screening-eligible patients completing a FIT within 12months; and cost, cost-effectiveness, and return on investment of the intervention.

conclusionsThis large-scale pragmatic trial will leverage electronic health record information and existing clinic staff to enroll a broad range of patients, including many with historically low colorectal-cancer screening rates. If successful, the program will provide a model for a cost-effective and scalable method to raise colorectal-cancer screening rates.

Indexed as

Research DesignAgedColonoscopyColorectal NeoplasmsCost-Benefit AnalysisEarly Detection of CancerElectronic Health RecordsFemaleHumansMaleMiddle AgedOccult BloodRisk FactorsSafety-net ProvidersSingle-Blind MethodCluster-randomized studyColorectal cancer screeningFecal immunochemical testPragmatic study

Identifiers

PMID24937017
PMCPMC4226652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.