ArticlePloS one2014
Immune response varies with rate of dispersal in invasive cane toads (Rhinella marina).
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Reduced Food Availability Amplifies Behavioral Depression and Impairs Locomotor Performance After Immune Challenge in Xenopus laevis.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Review
- The Microbiome of an Invasive Spider: Reduced Bacterial Richness, but no Indication of Microbial-Mediated Dispersal Behaviour.Microbial ecology · 2025Article
- Does a biological invasion modify host immune responses to parasite infection?Royal Society open science · 2025Article
- Does Motility-Restricting Fibrosis Influence Dispersal? An Experiment in Nature With Threespine Stickleback.Ecology and evolution · 2024Article
- Parasitic helminths of alien invasive anurans in Butuan City, Northeastern Mindanao, Philippines.Helminthologia · 2023Article
- A Call For More Ecologically And Evolutionarily Relevant Studies of Immune Costs.Evolutionary ecology · 2023Article
- Critical review of the phytohemagglutinin assay for assessing amphibian immunity.Conservation physiology · 2023Article
- Drosophila melanogaster hosts coevolving with Pseudomonas entomophila pathogen show sex-specific patterns of local adaptation.BMC ecology and evolution · 2022Article
- Microbiome of the Successful Freshwater Invader, the Signal Crayfish, and Its Changes along the Invasion Range.Microbiology spectrum · 2021Article
- Immune Response in Crayfish Is Species-Specific and Exhibits Changes along Invasion Range of a Successful Invader.Biology · 2021Article
- Recovery from discrete wound severities in side-blotched lizards (Uta stansburiana): implications for energy budget, locomotor performance, and oxidative stress.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021Article
- Increased immune marker variance in a population of invasive birds.Scientific reports · 2020Article
- Innate immunity of Florida cane toads: how dispersal has affected physiological responses to LPS.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020Article
- Not going with the flow: Locomotor activity does not constrain immunity in a wild fish.Ecology and evolution · 2019Article
- Immune and environment-driven gene expression during invasion: An eco-immunological application of RNA-Seq.Ecology and evolution · 2019Article
- Integrating time progression in ecoimmunology studies: beyond immune response intensity.Current zoology · 2019Article
- Cane toads (Rhinella marina) rely on water access, not drought tolerance, to invade xeric Australian environments.Oecologia · 2019Article
- The thermal dependency of locomotor performance evolves rapidly within an invasive species.Ecology and evolution · 2018Article
- Genetics of dispersal.Biological reviews of the Cambridge Philosophical Society · 2018Review
- The things they carried: The pathogenic effects of old and new parasites following the intercontinental invasion of the Australian cane toad (International journal for parasitology. Parasites and wildlife · 2017Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
What level of immunocompetence should an animal maintain while undertaking long-distance dispersal? Immune function (surveillance and response) might be down-regulated during prolonged physical exertion due to energy depletion, and/or to avoid autoimmune reactions arising from damaged tissue. On the other hand, heightened immune vigilance might be favored if the organism encounters novel pathogens as it enters novel environments. We assessed the links between immune defense and long-distance movement in a population of invasive cane toads (Rhinella marina) in Australia. Toads were radio-tracked for seven days to measure their activity levels and were then captured and subjected to a suite of immune assays. Toads that moved further showed decreased bacteria-killing ability in their plasma and decreased phagocytic activity in their whole blood, but a heightened skin-swelling response to phytohemagglutinin. Baseline and post-stress corticosterone levels were unrelated to distance moved. Thus, long-distance movement in cane toads is associated with a dampened response in some systems and enhanced response in another. This pattern suggests that sustained activity is accompanied by trade-offs among immune components rather than an overall down or up-regulation. The finding that high mobility is accompanied by modification of the immune system has important implications for animal invasions.
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