ReviewAmerican journal of translational research2014
In vivo optical imaging of cancer metastasis using multiphoton microscopy: a short review.
Review in American journal of translational research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Widefield frequency-domain autofluorescence lifetime imaging for detecting breast cancer in murine xenograft tumor tissues.Journal of biomedical optics · 2025Article
- Noninvasive and real-time monitoring of Au nanoparticle promoted cancer metastasis using in vivo flow cytometry.Biomedical optics express · 2021Article
- Live Intravital Intestine with Blood Flow Visualization in Neonatal Mice Using Two-photon Laser Scanning Microscopy.Bio-protocol · 2021Article
- Rho GTPase signalling networks in cancer cell transendothelial migration.Vascular biology (Bristol, England) · 2021Review
- Intravital Assessment of Blood Platelet Function. A Review of the Methodological Approaches with Examples of Studies of Selected Aspects of Blood Platelet Function.International journal of molecular sciences · 2020Review
- Live Imaging of Innate and Adaptive Immune Responses in the Liver.Frontiers in immunology · 2020Review
- Visualizing Oncolytic Virus-Host Interactions in Live Mice Using Intravital Microscopy.Molecular therapy oncolytics · 2018Article
- Analysis of adhesion kinetics of cancer cells on inflamed endothelium using a microfluidic platform.Biomicrofluidics · 2018Article
- Plasmonic Optical Imaging of Gold Nanorods Localization in Small Animals.Scientific reports · 2018Article
- Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay.Journal of visualized experiments : JoVE · 2018Article
- Identifying Two Common Types of Breast Benign Diseases Based on Multiphoton Microscopy.Scanning · 2018Article
- Agent-based model of angiogenesis simulates capillary sprout initiation in multicellular networks.Integrative biology : quantitative biosciences from nano to macro · 2015Article
- Layer-resolved colorectal tissues using nonlinear microscopy.Lasers in medical science · 2015Article
- Remodeling Components of the Tumor Microenvironment to Enhance Cancer Therapy.Frontiers in oncology · 2015Review
- Dynamic pathology for circulating free DNA in a dextran sodium sulfate colitis mouse model.Pediatric surgery international · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravital (in vivo) microscopy using fluorescently-tagged proteins is a valuable tool for imaging the expression of a specific protein, its subcellular location and the dynamics of specific cell populations in living animals. Recently, multiphoton microscopy including two-photon laser scanning microscopy (TPLSM) has been used in the field of tumor biology due to its ability to image target organs at higher magnification and at deeper depths from the tissue surface for longer time periods. We developed a method of in vivo real-time imaging for tumor metastasis using TPLSM with an organ stabilizing system, which allow us to observe not only a single tumor cell and its microenvironment for a long time, but also to observe the same organ of the same mouse at multiple time points in preclinical models. Here, we presented in vivo real-time images of 1) tumor cell arrest, 2) tumor cell-platelet interaction, 3) tumor cell-leukocyte interaction, and 4) metastatic colonization at the secondary organs as representative steps of metastatic process of experimental liver metastasis models using TPLSM.
Indexed as
Identifiers
24936213PMC4058302What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.