ReviewFrontiers in neurology2014
Glucose and the injured brain-monitored in the neurointensive care unit.
Review in Frontiers in neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- Multimodal neuromonitoring in the nordic countries: experiences and attitudes - a multi-institutional survey.Acta neurochirurgica · 2025Article
- Management Strategies Based on Multi-Modality Neuromonitoring in Severe Traumatic Brain Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Development of a model to predict the risk of cerebral infarction in acute vestibular syndrome.Heliyon · 2023Article
- Cerebral microdialysis and glucopenia in traumatic brain injury: A review.Frontiers in neurology · 2023Review
- Recent advances in molecular mechanisms of acute kidney injury in patients with diabetes mellitus.Frontiers in endocrinology · 2022Review
- Analysis of glucose metabolism byScientific reports · 2021Article
- Fine Tuning of Traumatic Brain Injury Management in Neurointensive Care-Indicative Observations and Future Perspectives.Frontiers in neurology · 2021Review
- Nutrition Therapy, Glucose Control, and Brain Metabolism in Traumatic Brain Injury: A Multimodal Monitoring Approach.Frontiers in neuroscience · 2020Review
- Neurobiology of Recovery of Motor Function after Stroke: The Central Nervous System Biomarker Effects of Constraint-Induced Movement Therapy.Neural plasticity · 2020Review
- High Arterial Glucose is Associated with Poor Pressure Autoregulation, High Cerebral Lactate/Pyruvate Ratio and Poor Outcome Following Traumatic Brain Injury.Neurocritical care · 2019Article
- Assessment of Metabolic and Nutritional Imbalance in Mechanically Ventilated Multiple Trauma Patients: From Molecular to Clinical Outcomes.Diagnostics (Basel, Switzerland) · 2019Review
- How to Translate Time: The Temporal Aspects of Rodent and Human Pathobiological Processes in Traumatic Brain Injury.Journal of neurotrauma · 2019Review
- On the detection of cerebral metabolic depression in experimental traumatic brain injury using Chemical Exchange Saturation Transfer (CEST)-weighted MRI.Scientific reports · 2018Article
- Influence of Admission Blood Glucose in Predicting Outcome in Patients With Spontaneous Intracerebral Hematoma.Frontiers in neurology · 2018Article
- Biochemical changes in the injured brain.World journal of biological chemistry · 2017Article
- Acute Kidney Injury in Diabetes Mellitus.International journal of nephrology · 2016Review
- What's New in Traumatic Brain Injury: Update on Tracking, Monitoring and Treatment.International journal of molecular sciences · 2015Review
- The emerging neuroprotective role of mitochondrial uncoupling protein-2 in traumatic brain injury.Translational neuroscience · 2015Review
- Analysis of the correlation between blood glucose level and prognosis in patients younger than 18 years of age who had head trauma.World journal of emergency surgery : WJES · 2015Article
- Interpretable machine learning for in-hospital mortality prediction in ICU patients with traumatic brain injury.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain has a continuous demand for energy that is met by oxidative metabolism of oxygen and glucose. This demand is compromised in the injured brain and if the inadequate supply persists it will lead to permanent tissue damage. Zero values of cerebral glucose have been associated with infarction and poor neurological outcome. Furthermore, hyperglycemia is common in patients with neurological insults and associated with poor outcome. Intensive insulin therapy (IIT) to control blood glucose has been suggested and used in neurointensive care with conflicting results. This review covers the studies reporting on monitoring of cerebral glucose with microdialysis in patients with traumatic brain injury (TBI), subarachnoid hemorrhage (SAH) and ischemic stroke. Studies investigating IIT are also discussed. Available data suggest that low cerebral glucose in patients with TBI and SAH provides valuable information on development of secondary ischemia and has been correlated with worse outcome. There is also indication that the location of the catheter is important for correlation between plasma and brain glucose. In conclusion considering catheter location, monitoring of brain glucose in the neurointensive care not only provides information on imminent secondary ischemia it also reveals the effect of peripheral treatment on the injured brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.