ArticleMicrobial ecology in health and disease2014
Higher blood glucose level associated with body mass index and gut microbiota in elderly people.
Article in Microbial ecology in health and disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Berberine-gut microbiota interactions based on CiteSpace: current research status and hotspots.Frontiers in microbiology · 2026Pooled it
- Alteration in Gut Microbiota Composition of Older Adults Is Associated with Obesity and Its Indices: A Systematic Review.The journal of nutrition, health & aging · 2023Pooled it
- Differences in Glycemic Abnormalities Between Primary Aldosteronism and Essential Hypertension: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2022Pooled it
- Vitamin D Status and Selected Metabolic Parameters in Salt Mine Workers: A Cross-Sectional Study.Nutrients · 2026Article
- Bioactive Component Screening and Mechanistic Study of the Anti-Diabetic Activity ofCurrent issues in molecular biology · 2025Article
- Association of hemoglobin levels with metabolic traits in women with PCOS.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Metabolic Syndrome: A Narrative Review from the Oxidative Stress to the Management of Related Diseases.Antioxidants (Basel, Switzerland) · 2023Review
- Links between Diet, Intestinal Anaerobes, Microbial Metabolites and Health.Biomedicines · 2023Review
- Industrial and Ruminant Trans-Fatty Acids-Enriched Diets Differentially Modulate the Microbiome and Fecal Metabolites in C57BL/6 Mice.Nutrients · 2023Article
- The correlation of the fecal microbiome with the biochemical profile during menopause: a Brazilian cohort study.BMC women's health · 2022Article
- Article
- A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19.Frontiers in public health · 2021Article
- Relationship Between Modified Body Adiposity Index and A Body Shape Index with Biochemical Parameters in Bariatric Surgery Candidates.Obesity surgery · 2020Article
- Characterization of the Gut Microbiota of Individuals at Different T2D Stages Reveals a Complex Relationship with the Host.Microorganisms · 2020Article
- Effects of Berberine on the Gastrointestinal Microbiota.Frontiers in cellular and infection microbiology · 2020Review
- Article
- Age-stratified comparative analysis of the differences of gut microbiota associated with blood glucose level.BMC microbiology · 2019Article
- Analysis of gut microbiota of obese individuals with type 2 diabetes and healthy individuals.PloS one · 2019Article
- Dissecting cause and effect in host-microbiome interactions using the combined worm-bug model system.Biogerontology · 2018Article
- Hypoglycemic Mechanism of the Berberine Organic Acid Salt under the Synergistic Effect of Intestinal Flora and Oxidative Stress.Oxidative medicine and cellular longevity · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome dominant bacterial divisions of the intestines have been linked to metabolic diseases such as overweight and diabetes.
objectiveA pilot study aimed to evaluate the relations between the culturable intestinal bacteria with body mass index (BMI) and some principal cellular and metabolic markers of blood in people older than 65.
designAltogether 38 generally healthy elderly people were recruited: ambulatory (n=19) and orthopedic surgery (n=19). Questionnaires on general health, anthropometric measurements, routine clinical and laboratory data, and quantitative composition of cultivable gut microbiota were performed.
resultsBlood glucose level was positively correlated with BMI (r=0.402; p=0.014). Higher blood glucose level had negative correlation with relative share of intestinal anaerobic bacteria such as bacteroides (r=-0.434; p=0.0076) and gram-positive anaerobic cocci (r=-0.364; p=0.027). In contrast, the relative share of bifidobacteria (r=0.383; p=0.019) and staphylococci (r=0.433; p=0.008) was positively correlated to blood glucose level. In elderly people, a higher blood glucose concentration was predicted by the reduction of the anaerobes' proportion (adj. sex, age, and BMI R(2)=0.192, p=0.028) and that of Bacteroides sp. (adj. R(2)=0.309, p=0.016).
conclusionA tight interplay between increased BMI, level of blood glucose, and the reduced proportion of cultivable bacteroides is taking place in the gut microbiota of elderly people.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.