ArticleInternational journal of medical sciences2014
Screening tests using serum tissue transglutaminase IgA may facilitate the identification of undiagnosed celiac disease among Japanese population.
Article in International journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Celiac Disease Genetics, Pathogenesis, and Standard Therapy for Japanese Patients.International journal of molecular sciences · 2023Review
- Evaluation of a Bi-Analyte Immunoblot as a Useful Tool for Diagnosing Dermatitis Herpetiformis.Diagnostics (Basel, Switzerland) · 2021Article
- Serological screening for celiac disease in adults in Japan: Shimane CoHRE study.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Diagnosis and Treatment Patterns in Celiac Disease.Digestive diseases and sciences · 2019Review
- Successful Empiric Therapy for Postsplenectomy Sepsis with Campylobacter fetus in an Abattoir Worker with Follicular Lymphoma.Internal medicine (Tokyo, Japan) · 2018Article
- A Caucasian American patient with celiac disease diagnosed in Japan and successfully treated with a gluten-free diet.Clinical journal of gastroenterology · 2018Article
- Prevalence of Adult Celiac Disease in India: Regional Variations and Associations.The American journal of gastroenterology · 2016Article
- The importance of anti-transglutaminase IgA antibody detection in the diagnosis of celiac disease - case report of an inappropriate diagnostic approach.Przeglad gastroenterologiczny · 2015Article
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of celiac disease (CD) among Japanese population has been unknown, whereas it has been increasingly recognized in the US and in the European countries. The aim of the present study is to identify possible cases with CD among Japanese population and clarify the relevance of screening for the disease. We conducted a serologic screening for the disease among 710 Japanese patients and 239 healthy volunteers at a local tertiary teaching hospital, using an anti-tissue transglutaminase IgA (TTG-IgA) test, and histological examination of the small intestines from the TTG-IgA positive subjects. There were no TTG-IgA positive sera among the healthy volunteers. Twenty of the patients (2.8%), including eight with malignant lymphoma, were tested positive for TTG-IgA. The histological examination of the eleven patients among those with positive TTG-IgA, seven showed villous atrophy and partial lymphocytes infiltration in the mucosa, which could be compatible to mucosal changes observed in CD. Five of them had non-Hodgkin lymphoma in the gastrointestinal tracts. Serologic tests using TTG-IgA might be relevant to screen for those with undiagnosed CD among Japanese population.
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