Evidence map›Paper›PMID 24936090›Full record

Trial reportSexually transmitted infections2015

The clinical and cost-effectiveness of brief advice for excessive alcohol consumption among people attending sexual health clinics: a randomised controlled trial.

Mike J Crawford, Rahil Sanatinia, Barbara Barrett, Sarah Byford, Madeleine Dean, John Green, Rachael Jones, Baptiste Leurent, Michael J Sweeting, Robin Touquet and 4 more

Open access · hybridAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Sexually transmitted infections, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Effectiveness of brief alcohol interventions in primary care populations.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Review
  8. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Mike J CrawfordCentre for Mental Health, Imperial College, London, UK.
Rahil SanatiniaCentre for Mental Health, Imperial College, London, UK.
Barbara BarrettCentre for the Economics of Mental and Physical Health, King's College London, London, UK.
Sarah ByfordCentre for the Economics of Mental and Physical Health, King's College London, London, UK.
Madeleine DeanCentre for Mental Health, Imperial College, London, UK.
John GreenCentral and North West London NHS Foundation Trust, London, UK.
Rachael JonesChelsea and Westminster Hospital NHS Foundation Trust, London, UK.
Baptiste LeurentPRIMENT Clinical Trials Unit, University College, London, UK.
Michael J SweetingMRC Biostatistics Unit, Cambridge, UK.
Robin TouquetImperial College Healthcare NHS Trust, London, UK.
Linda GreeneImperial College Healthcare NHS Trust, London, UK.
Peter TyrerCentre for Mental Health, Imperial College, London, UK.
Helen WardSchool of Public Health, Imperial College, London, UK.
Anne Lingford-HughesCentre for Neuropsychopharamacology, Imperial College, London, UK.
Imperial College London · GBCentre for Mental Health · GBImperial College Healthcare NHS Trust · GBKing's College London · GBCentral and North West London NHS Foundation Trust · GBChelsea and Westminster Hospital NHS Foundation Trust · GBMRC Biostatistics Unit · GBUniversity College London · GB

Funding

British Heart Foundation RG/08/014/24067Department of Health 09/91/04Medical Research Council G0300712Medical Research Council MR/L003120/1
6 · The paper itself

Abstract

objectivesTo examine the clinical and cost-effectiveness of brief advice for excessive alcohol consumption among people who attend sexual health clinics.

methodsTwo-arm, parallel group, assessor blind, pragmatic, randomised controlled trial. 802 people aged 19 years or over who attended one of three sexual health clinics and were drinking excessively were randomised to either brief advice or control treatment. Brief advice consisted of feedback on alcohol and health, written information and an offer of an appointment with an Alcohol Health Worker. Control participants received a leaflet on health and lifestyle. The primary outcome was mean weekly alcohol consumption during the previous 90 days measured 6 months after randomisation. The main secondary outcome was unprotected sex during this period.

resultsAmong the 402 randomised to brief advice, 397 (99%) received it. The adjusted mean difference in alcohol consumption at 6 months was -2.33 units per week (95% CI -4.69 to 0.03, p=0.053) among those in the active compared to the control arm of the trial. Unprotected sex was reported by 154 (53%) of those who received brief advice, and 178 (59%) controls (adjusted OR=0.89, 95% CI 0.63 to 1.25, p=0.496). There were no significant differences in costs between study groups at 6 months.

conclusionsIntroduction of universal screening and brief advice for excessive alcohol use among people attending sexual health clinics does not result in clinically important reductions in alcohol consumption or provide a cost-effective use of resources. TRIAL REGISTRATION NUMBER: Current Controlled Trials ISRCTN 99963322.

Indexed as

AdultAlcohol DrinkingCost-Benefit AnalysisFemaleHealth EducationHumansMaleSexual BehaviorSexually Transmitted DiseasesTreatment OutcomeYoung AdultClinical TrialsSexual BehaviourSubstance Misuse

Identifiers

PMID24936090
PMCPMC4316933
OpenAlexW2125048985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.